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rapid diagnostic tests (RDTs)

Clinical performance of an automated reader in interpreting malaria rapid diagnostic tests in Tanzania

April 25, 2013 - 13:24 -- Open Access
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Author(s): 
Shekalaghe S, Cancino M, Mavere C, Juma O, Mohammed A, Abdulla S, Ferro S
Reference: 
Malaria Journal 2013, 12:141 (24 April 2013)
MalariaWorld

The sensitivity and specificity of the DekiReader in interpretation of SD RDTs were comparable to previous reports and showed high agreement to visual interpretation (>98%).

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Rapid diagnostic tests for molecular surveillance of Plasmodium falciparum malaria -assessment of DNA extraction methods and field applicability

March 21, 2013 - 06:57 -- Open Access
Author(s): 
Morris U, Aydin-Schmidt B, Shakely D, Mårtensson A, Jörnhagen L, Ali AS, Msellem MI, Petzold M, Gil JP, Ferreira P, Björkman A
Reference: 
Malaria Journal 2013, 12:106 (19 March 2013)
MalariaWorld

The results support RDT as a valuable source of parasite DNA and provide evidence for RDT-DNA extraction for improved malaria case detection, molecular drug resistance surveillance, and RDT quality control.

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Evaluation of the OnSite (Pf/Pan) rapid diagnostic test for diagnosis of clinical malaria

December 19, 2012 - 06:15 -- Open Access
Author(s): 
Mohon A, Elahi R, Podder M, Mohiuddin K, Hossain M, Khan WA, Haque R, Alam M
Reference: 
Malaria Journal 2012, 11:415 (12 December 2012)
MalariaWorld

The new OnSite (Pf/Pan) RDT is both sensitive and specific for symptomatic malaria diagnosis in standard laboratory conditions.

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Malaria rapid diagnostic test transport and storage conditions in Burkina Faso, Senegal, Ethiopia and the Philippines

December 10, 2012 - 08:38 -- Open Access
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Author(s): 
Albertini A, Lee E, Coulibaly SO, Sleshi M, Faye B, Mationg ML, Ouedraogo K, Tsadik AG, Feleke SM, Diallo I, Gaye O, Luchavez J, Bennett J, Bell D
Reference: 
Malaria Journal 2012, 11:406 (6 December 2012)
MalariaWorld

Malaria RDTs were regularly exposed to temperatures above recommended limits for many commercially-available RDTs and other medical commodities such as drugs, but rarely exceeded the recommended storage limits for particular products in use in these countries.

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Genetic variation in histidine rich proteins among Indian Plasmodium falciparum population: possible cause of variable sensitivity malaria of rapid diagnostic tests

August 30, 2012 - 08:05 -- Kabogo Ndegwa
Author(s): 
Kumar N, Singh JP, Pande V, Mishra N, Srivastava B, Kapoor R, Valecha N, Anvikar AR
Reference: 
Malaria Journal 2012, 11:298 (28 August 2012)

MalariaWorldThe results provide insights into the genetic diversity of Pfhrp2 and Pfhrp3 genes among Indian P. falciparum population and its relation to RDT sensitivity.

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Increased use of malaria rapid diagnostic tests improves targeting of anti-malarial treatment in rural Tanzania: implications for nationwide rollout of malaria rapid diagnostic tests

July 5, 2012 - 14:31 -- Kabogo Ndegwa
Author(s): 
Masanja IM, Selemani M, Amuri B, Kajungu D, Khatib R, Kachur S, Skarbinski J
Reference: 
Malaria Journal 2012, 11:221 (2 July 2012)

MalariaWorldImplementation of RDTs increased use of RDTs for parasitological confirmation and reduced over-treatment with ACT during high malaria transmission season in one area in Tanzania.

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Open Access | Using community-owned resource persons to provide early diagnosis and treatment and estimate malaria burden at community level in north-eastern Tanzania

May 9, 2012 - 07:24 -- Kabogo Ndegwa
Author(s): 
Rutta AS, Francis F, Mmbando BP, Ishengoma DS, Sembuche SH, Malecela EK, Sadi JY, Kamugisha ML, Lemnge MM
Reference: 
Malaria Journal 2012, 11:152 (3 May 2012)

MalariaWorldWith basic training, supervision and RDTs, CORPs successfully provided early diagnosis and treatment and reduced consumption of anti-malarials.

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Open Access | Management of uncomplicated malaria in febrile under five-year-old children by community health workers in Madagascar: reliability of malaria rapid diagnostic tests

March 29, 2012 - 09:37 -- Kabogo Ndegwa
Author(s): 
Ratsimbasoa A, Ravony H, Vonimpaisomihanta J, Raherinjafy R, Jahevitra M, Rapelanoro R, Rakotomanga J, Malvy D, Millet P, Menard D
Reference: 
Malaria Journal 2012, 11:85 (25 March 2012)

MalariaWorldIntroduction of easy-to-use diagnostic tools, such as RDTs, at the community level appears to be an effective strategy for improving febrile patient management and for reducing excessive use of anti-malarial drugs.

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Open Access | Rapid diagnostic tests as a source of DNA for Plasmodium species-specific real-time PCR

March 28, 2011 - 12:22 -- Kabogo Ndegwa
Author(s): 
Cnops L, Boderie M, Gillet P, Van Esbroeck M, Jacobs J
Reference: 
Malaria Journal 2011, 10:67 (24 March 2011)

RDTs are a reliable source of DNA for Plasmodium real-time PCR. This study demonstrates the best method of RDT fragment sampling for a wide range of RDT brands in combination with a simple and low cost extraction method, allowing RDT quality control.

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