The interpretation of RDT results requires some training but is a good alternative to the FST.
rapid diagnostic tests (RDTs)
RDTs remain positive for a highly variable amount of time after treatment with anti-malarials, and the duration of positivity is highly dependent on the type of RDT used for diagnosis.
The Deki Reader is likely a useful tool for malaria diagnosis, treatment, and real-time data management.
Surveillance of pfhrp2- and pfhrp3-negative P. falciparum requires careful laboratory workflows. PCR-based testing methods coupled with microscopy and/or antigen testing serve as useful tools to support policy development.
This study revealed the global genetic variation of the ldh gene in P. falciparum, providing knowledge for improving detection of LDH-based RDTs and supporting the candidacy of LDH as a therapeutic drug target.
The low prevalence of pfhrp2 deletions suggests that RDTs will detect the vast majority of the P. falciparum infections.
Reactive strategies in southern Zambia yield improved identification of the parasite reservoir when targeted to areas with prevalence less than 10%.
In this setting G6PD RDTs could avert DALYs by reducing recurrences and reducing hemolytic risk in G6PD deficient patients at low costs or cost savings.
The results reveal important differences between provinces.
The PRIME intervention did not have the desired impact on inappropriate treatment of malaria for children under five.