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malaria rapid diagnostic tests (RDTs)

Isolation and characterization of malaria PfHRP2 specific VNAR antibody fragments from immunized shark phage display library

October 30, 2018 - 15:34 -- Open Access
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Author(s): 
Chiuan Herng Leow, Katja Fischer, Chiuan Yee Leow, Katleen Braet, Qin Cheng and James McCarthy
Reference: 
Malaria Journal 2018 17:383, 24 October 2018

Target-specific bacteriophage VNARs were successfully isolated after a series of immunization, demonstrating that phage display technology is a useful tool for selection of antigen binders.

Implementation of a malaria rapid diagnostic test in a rural setting of Nanoro, Burkina Faso: from expectation to reality

September 4, 2018 - 15:49 -- Open Access
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Author(s): 
Francois Kiemde, Marc Christian Tahita, Massa dit Achille Bonko, Petra F. Mens, Halidou Tinto, Michael Boele van Hensbroek and Henk D. F. H. Schallig
Reference: 
Malaria Journal 2018 17:316, 30 August 2018

Malaria RDT testing performed at the participating rural health facilities resulted in more malaria false positives compared to those performed at central laboratory.

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Reuse of malaria rapid diagnostic tests for amplicon deep sequencing to estimate Plasmodium falciparum transmission intensity in western Uganda

July 17, 2018 - 16:06 -- Open Access
Author(s): 
Ross M. Boyce, Nick Hathaway, Jonathan J. Juliano, et al.
Reference: 
Scientific Reportsvolume 8, Article number: 10159 (2018)

Molecular techniques are not routinely employed for malaria surveillance, while cross-sectional, community-based parasite surveys require significant resources.

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Evaluation of malaria rapid diagnostic test (RDT) use by community health workers: a longitudinal study in western Kenya

May 22, 2018 - 14:02 -- Open Access
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Author(s): 
Matthew R. Boyce, Diana Menya, Elizabeth L. Turner, Jeremiah Laktabai and Wendy Prudhomme-O’Meara
Reference: 
Malaria Journal 2018 17:206, 18 May 2018

With training, most CHWs performing RDTs maintain diagnostic testing competency over at least 12 months.

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Fever case management at private health facilities and private pharmacies on the Kenyan coast: analysis of data from two rounds of client exit interviews and mystery client visits

March 15, 2018 - 06:58 -- Open Access
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Author(s): 
Stephen Poyer, Anne Musuva, Nicole Charman, et al.
Reference: 
Malaria Journal 2018 17:112, 13 March 2018

Non-laboratory staff working in registered pharmacies in Kenya can follow national guidelines for diagnosis with RDTs when provided with the same level of training and supervision as private health facility staff.

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The inverted cup device for blood transfer on malaria RDTs: ease of use, acceptability and safety in routine use by health workers in Nigeria

January 16, 2018 - 16:03 -- Open Access
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Author(s): 
Sandra Incardona, Magoma Mwancha-Kwasa, Roxanne R. Rees-Channer, Audrey Albertini, Joshua Havumaki, Peter Chiodini, Wellington Oyibo and Iveth J. Gonzalez
Reference: 
Malaria Journal 2018 17:29, 15 January 2018

The good volume accuracy and high acceptability of the inverted cup device shown in this study, along with observed ease of use and safety in hands of health workers, further strengthens prior findings which demonstrated its higher accuracy as compared with other BTDs in a laboratory setting

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Stabilization of RDT target antigens present in dried Plasmodium falciparum-infected samples for validating malaria rapid diagnostic tests at the point of care

January 9, 2018 - 16:13 -- Open Access
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Author(s): 
Collins Morang’a, Cyrus Ayieko, George Awinda, Rachel Achilla, Caroline Moseti, Bernhards Ogutu, John Waitumbi and Elizabeth Wanja
Reference: 
Malaria Journal 2018 17:10, 8 January 2018

These findings confirm that stabilizing RDT target antigens in dried P. falciparum-infected samples using chemical additives provides field-stable positive controls for malaria RDTs.

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Global survey of malaria rapid diagnostic test (RDT) sales, procurement and lot verification practices: assessing the use of the WHO–FIND Malaria RDT Evaluation Programme (2011–2014)

May 16, 2017 - 15:01 -- Open Access
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Author(s): 
Sandra Incardona, Elisa Serra-Casas, Nora Champouillon, Christian Nsanzabana, Jane Cunningham and Iveth J. González
Reference: 
Malaria Journal 2017 16:196, 15 May 2017

This survey provided in-depth information on RDT sales and procurement dynamics, including the largely unstudied private sector, and demonstrated how the WHO–FIND Programme has positively influenced procurement practices in the public sector.

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Assessment of the utility of a symptom-based algorithm for identifying febrile patients for malaria diagnostic testing in Senegal

March 9, 2017 - 14:42 -- Open Access
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Author(s): 
Julie Thwing, Fatou Ba, Mady Ba, et al.
Reference: 
Malaria Journal 2017 16:95, 1 March 2017

In all but the lowest malaria transmission zone, use of the algorithm excludes an unacceptably large proportion of patients with malaria from receiving an RDT at their first visit, denying them timely diagnosis and treatment.

Exploring health practitioners’ acceptability of a prospective semi-quantitative pfHRP2 device to define severe malaria in the Democratic Republic of Congo

December 22, 2015 - 16:57 -- Open Access
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Author(s): 
Freek de Haan, Marie Onyamboko, Caterina Fanello, Charles Woodrow, Yoel Lubell, Wouter Boon, Arjen Dondorp
Reference: 
Malaria Journal 2015, 14:503 (15 December 2015)

Congolese practitioners perceive the prospective semi-quantitative pfHRP2 device as a welcome addition to their clinical equipment.

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