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genetic

Open Access | High recombination rates and hotspots in a Plasmodium falciparum genetic cross

April 6, 2011 - 12:52 -- Patrick Sampao
Author(s): 
Hongying Jiang, Na Li, Xin-zhuan Su, et al.
Reference: 
Genome Biology 2011, 12:R33

Here, we used a high-density tiling array to estimate the genetic recombination rate among 32 progeny of a P. falciparum genetic cross (7G8 x GB4). We detected 638 recombination events and constructed a high-resolution genetic map.

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Multilocus nuclear DNA markers and genetic parameters in an Indian Anopheles minimus population

March 31, 2011 - 12:28 -- Patrick Sampao
Author(s): 
Jyotsana Dixit, Hemlata Srivastava, O.P. Singh, D.N. Saksena, Aparup Das
Reference: 
Infection, Genetics and Evolution, Volume 11, Issue 3, April 2011, Pages 572-579

Considering malaria is a highly fatal vector-borne infectious disease, inference on population genetic structure and demography could be of help in the long run for malaria vector management and control. Using the published genome sequence information of Anopheles gambiae we designed EPIC primers

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Open Access | Genetic Structure of Plasmodium falciparum and Elimination of Malaria, Comoros Archipelago

October 26, 2010 - 11:45 -- Patrick Sampao
Author(s): 
Stanislas R., Hervé B., et al.
Reference: 
Emerging Infectious Diseases, Volume 16, Number 11–November 2010

To assess the relevance of such a local strategy, we performed a population genetics analysis by using multilocus microsatellite and resistance genotyping of Plasmodium falciparum sampled from each island of the archipelago.

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Open Access | Commentary: Genome-wide association studies in Plasmodium species

July 15, 2010 - 09:43 -- Patrick Sampao
Author(s): 
Bridget Penman, Caroline Buckee, Sunetra Gupta and Sean Nee
Reference: 
BMC Biology 2010, 8:90

A recent study in BMC Genetics has found that populations of the malaria parasite Plasmodium vivax should be amenable to GWAS searching for a genetic basis of parasite pathogenicity.

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