The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10204 malaria professionals are enjoying the free benefits of MalariaWorld today

ACT

Open Access | Knowledge and behaviour as determinants of anti-malarial drug use in a peri-urban population from malaria holoendemic region of western Kenya

April 23, 2011 - 08:32 -- Kabogo Ndegwa
Author(s): 
Carren A Watsierah, Walter GZO Jura, Evans Raballah, Dan Kaseje, Benard Abong'o, Collins Ouma
Reference: 
Malaria Journal 2011, 10:99 (20 April 2011)

Majority of consumers in the study area were knowledgeable on the symptoms of malaria.

Country: 
Medical Condition: 
Medical Treatment: 

Open Access | Low prevalence of Plasmodium falciparum antigenaemia among asymptomatic HAART-treated adults in an urban cohort in Uganda

March 23, 2011 - 08:48 -- Kabogo Ndegwa
Author(s): 
Nakanjako D, Kiragga AN, Castelnuovo B, Kyabayinze DJ, Kamya MR
Reference: 
Malaria Journal 2011, 10:66 (22 March 2011)

In an urban area of low to moderate stable malaria transmission, there was low HRP2 P. falciparum antigenaemia among PLHIV after long-term HAART and cotrimoxazole prophylaxis.

Person: 
Country: 
Medical Condition: 
Medical Treatment: 

Open Access | Brazilian Plasmodium falciparum isolates: investigation of candidate polymorphisms for artemisinin resistance before introduction of artemisinin-based combination therapy

December 14, 2010 - 06:25 -- Kabogo Ndegwa
Author(s): 
Gama BE, Almeida-de-Oliveira NK, de Souza JM, Santos F, de Carvalho LJ, Melo YF, Rosenthal PJ, Daniel-Ribeiro CT, Ferreira-da-Cruz M
Reference: 
Malaria Journal 2010, 9:355 (8 December 2010)

Although some polymorphism in pfmdr1 and pfatpase6 were verified, no reported haplotypes in both genes that may mediate altered response to ACT was detected before the introduction of this therapy in Brazil.

Country: 
Medical Treatment: 

Is parasite clearance clinically important after malaria treatment in a high transmission area? A 3-month follow-up of home-based management with herbal medicine or ACT

December 9, 2010 - 12:13 -- Patrick Sampao
Author(s): 
Merlin L. Willcox, Bertrand Graz, Chiaka Diakite, Jacques Falquet, Florent Dackouo, Oumar Sidibe, Sergio Giani, Drissa Diallo
Reference: 
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 105, Issue 1, January 2011, Pages 23-31

This study, in a high transmission area of South Mali, explores whether residual parasitaemia at day 28 was associated with subsequent malaria episodes and/or anaemia.

Medical Condition: 
Medical Treatment: 

Open Access | Changing malaria intervention coverage, transmission and hospitalization in Kenya

October 22, 2010 - 06:30 -- Kabogo Ndegwa
Author(s): 
Okiro EA, Alegana VA, Noor AM, Snow RW
Reference: 
Malaria Journal 2010, 9:285 (15 October 2010)

This study provides evidence of significant within and between location heterogeneity in temporal trends of malaria disease burden. Plausible drivers for changing disease incidence suggest a complex combination of mechanisms, not easily measured retrospectively.

Continent: 
Country: 
Medical Condition: 
Medical Treatment: 

Open Access | Reducing Plasmodium falciparum Malaria Transmission in Africa: A Model-Based Evaluation of Intervention Strategies

August 11, 2010 - 13:27 -- Kabogo Ndegwa
Author(s): 
Jamie T. Griffin, T. Deirdre Hollingsworth, Lucy C. Okell, Thomas S. Churcher, Michael White, Wes Hinsley, Teun Bousema, Chris J. Drakeley, Neil M. Ferguson, María-Gloria Basáñez, Azra C. Ghani
Reference: 
PLoS Med 7(8): e1000324

Interventions using current tools can result in major reductions in P. falciparum malaria transmission and the associated disease burden in Africa.

Continent: 
Medical Treatment: 

Arterolane, a New Synthetic Trioxolane for Treatment of Uncomplicated Plasmodium falciparum Malaria: A Phase II, Multicenter, Randomized, Dose-Finding Clinical Trial

August 10, 2010 - 09:38 -- Kabogo Ndegwa
Tags: 
Author(s): 
N Valecha, S Looareesuwan, A Martensson, SM Abdulla, S Krudsood, N Tangpukdee, S Mohanty, SK Mishra, PK Tyagi, SK Sharma, J Moehrle, A Gautam, A Roy, JK Paliwal, M Kothari, N Saha, AP Dash, A örkman
Reference: 
Clinical Infectious Diseases 2010;51:000–000

Arterolane at daily doses of 100 and 200 mg is a rapidly acting, effective, and safe synthetic antimalarial drug, which may potentially represent an alternative to artemisinin derivatives in antimalarial combination therapy.

Medical Condition: 
Medical Treatment: 

Fixed artesunate-amodiaquine combined pre-formulation study for the treatment of malaria

July 20, 2010 - 08:07 -- Kabogo Ndegwa
Tags: 
Author(s): 
T Kauss, F Fawaz, M Guyot, AM Lagueny, I dos Santos, F Bonini, P Olliaro, A Caminiti, P Millet
Reference: 
International Journal of Pharmaceutics, Volume 395, Issues 1-2, 16 August 2010, Pages 198-204

Artemisinin-based combination therapies, including artesunate (AS) + amodiaquine (AQ), are the currently recommended first-line treatment of uncomplicated falciparum malaria. Fixed-dose co-formulations offer logistic and adherence advantages.

Medical Condition: 
Medical Treatment: 

Open Access | Community acceptability of use of rapid diagnostic tests for malaria by community health workers in Uganda

July 14, 2010 - 12:54 -- Kabogo Ndegwa
Author(s): 
Mukanga D, Tibenderana JK, Kiguli J, Pariyo GW, Waiswa P, Bajunirwe F, Mutamba B, Counihan H, Ojiambo G, Kallander K
Reference: 
Malaria Journal 2010, 9:203 (13 July 2010)

Use of RDTs by CMDs is likely to be acceptable by community members given that CMDs are properly trained, and receive regular technical supervision and logistical support. A well-designed behaviour change communication strategy is needed to address the anticipated programmatic challenges as well as community fears and stigma about drawing blood.

Person: 
Country: 
Medical Condition: 

Open Access | Use of RDTs to improve malaria diagnosis and fever case management at primary health care facilities in Uganda

July 13, 2010 - 14:54 -- Kabogo Ndegwa
Author(s): 
Kyabayinze DJ, Asiimwe C, Nakanjako D, Nabakooza J, Counihan H, Tibenderana JK
Reference: 
Malaria Journal 2010, 9:200 (12 July 2010)

Use of RDTs resulted in a 2-fold reduction in anti-malarial drug prescription at LLHCFs. The study demonstrated that RDT use is feasible at LLHCFs, and can lead to better targetting of malaria treatment.

Country: 
Medical Condition: 
Medical Treatment: 

Pages

Subscribe to RSS - ACT