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medicine

How Not To Control Malaria

May 11, 2012 - 11:28 -- Patrick Sawa
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The cost of endemic malaria to Africa is overwhelming. Yet the effects of the disjointed, unfocused and mainly misdirected control efforts are visible and significant. We saw 216 Million case of malaria in 2011 and had 650000 deaths due to malaria in the same timeframe. When compared with almost 250 Million cases and 863000 deaths just a short three years earlier, the effect is clear. In spite of the plethora of effective tools available to us, the elimination of malaria will largely remain a pie in the sky.

Is parasite clearance clinically important after malaria treatment in a high transmission area? A 3-month follow-up of home-based management with herbal medicine or ACT

December 9, 2010 - 12:13 -- Patrick Sampao
Author(s): 
Merlin L. Willcox, Bertrand Graz, Chiaka Diakite, Jacques Falquet, Florent Dackouo, Oumar Sidibe, Sergio Giani, Drissa Diallo
Reference: 
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 105, Issue 1, January 2011, Pages 23-31

This study, in a high transmission area of South Mali, explores whether residual parasitaemia at day 28 was associated with subsequent malaria episodes and/or anaemia.

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Open Access | Oral Presentation: Refreshed approaches to the therapy of malaria - the case of natural medicine

November 8, 2010 - 09:36 -- Patrick Sampao
Author(s): 
Hagai Ginsburg
Reference: 
Malaria Journal 2010, 9(Suppl 2):O16 (20 October 2010)

This disappointment and the successful use of natural compounds emerging from traditional medicine for the chemotherapy of malaria (quinine, artemisnin) have invigorated the search for new antimalarials from natural sources. Hundreds of thousands compounds were screened and some promising leads were identified.

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Open Access | Factors influencing implementation of the Ministry of Health-led private medicine retailer programmes on malaria in Kenya

March 7, 2010 - 09:42 -- Ingeborg van Schayk
Author(s): 
Rowa Y, Abuya TO, Mutemi WK, Ochola S, Molyneux C, Marsh V
Reference: 
BMC Public Health 2010, 10:93 (24 February 2010)

This study explored stakeholders' perceptions of the role of private medicine retailers (PMRs), the value and feasibility of programme goals, perceived programme impact, factors influencing implementation and recommendations in three districts of Kenya.

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Review: New medicines to improve control and contribute to the eradication of malaria

November 13, 2009 - 09:38 -- Ingeborg van Schayk
Author(s): 
Timothy N. C. Wells, Pedro L. Alonso & Winston E. Gutteridge
Reference: 
Nature Reviews Drug Discovery 8, 879-891 (November 2009)

Recent advances in genome-based technologies and in in vitro screening of whole parasites have broadened the range of therapeutic targets and are accelerating the development of a new generation of treatments for both malaria control and eradication.

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