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resistance

Open Access | Global Trends in the Use of Insecticides for Vector-borne Disease Control

January 23, 2012 - 09:30 -- Kabogo Ndegwa
Author(s): 
Henk van den Berg, Morteza Zaim, Rajpal Singh Yadav, Agnes Soares, Birkinesh Ameneshewa, Abraham Mnzava, Jeffrey Hii, Aditya Prashad Dash, Mikhail Ejov
Reference: 
Environmental Health Perspectives

MalariaWorldThe global use of DDT has not changed substantially since the Stockholm Convention entered into force.

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Approximations for the hitchhiking effect caused by the evolution of antimalarial-drug resistance

July 19, 2010 - 13:40 -- Kabogo Ndegwa
Author(s): 
KA Schneider, Y Kim
Reference: 
Journal of Mathematical Biology, July 11, 2010

An analytically feasible, deterministic model for the spread of drug resistance among human malaria parasites, which incorporates all characteristics of the complex malaria-transmission cycle was introduced by Schneider and Kim (Theor. Popul Biol, 2010).

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Open Access | Perspective: Extensive Drug Resistance in Malaria and Tuberculosis

July 6, 2010 - 06:41 -- Kabogo Ndegwa
Author(s): 
Chansuda Wongsrichanalai, Comments to Author Jay K. Varma, Jonathan J. Juliano, Michael E. Kimerling, and John R. MacArthur
Reference: 
Emerg Infect Dis, Volume 16, Number 7–July 2010

Drug resistance in malaria and in tuberculosis (TB) are major global health problems. Although the terms multidrug-resistant TB and extensively drug-resistant TB are precisely defined, the term multidrug resistance is often loosely used when discussing malaria.

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Spatio-Temporal Patterns in kdr Frequency in Permethrin and DDT Resistant Anopheles gambiae s.s. from Uganda

April 13, 2010 - 09:11 -- Patrick Sampao
Author(s): 
Katrijn Verhaeghen, Wim Van Bortel, Patricia Roelants, Paul Edward Okello, Ambrose Talisuna, AND Marc Coosemans
Reference: 
American Journal of Tropical Medicine Hygiene, Vol 82: 4, pp. 566-573

In the dry season, the kdr frequency was significantly higher in Plasmodium falciparum-infected mosquitoes, indicating that mosquitoes bearing a kdr mutation have a better adult survival, hence a higher likelihood of becoming infectious.

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Open Access | Chloroquine reduces arylsulphatase B activity and increases chondroitin 4-sulphate: implications for mechanisms of action and resistance

December 23, 2009 - 21:42 -- Ingeborg van Schayk
Author(s): 
Sumit Bhattacharyya, Kemal Solakyildirim, Zhenqing Zhang, Robert J Linhardt, Joanne K Tobacman
Reference: 
Malaria Journal 2009, 8:303 (17 December 2009)

If chloroquine reduced ASB activity, leading to increased chondroitin-4-sulphation, it was hypothesized that the anti-malarial mechanism of chloroquine might derive, at least in part, from suppression of ASB.

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Antimicrobial Agents: Global resistance surveillance: ensuring antimalarial efficacy in the future

October 31, 2009 - 10:39 -- Ingeborg van Schayk
Author(s): 
Guerin, Philippe J; Bates, Sarah J; Sibley, Carol H
Reference: 
Current Opinion in Infectious Diseases. 22(6):593-600, December 2009

This review summarizes the current status and the challenges to effective surveillance, and suggests approaches for improvement.

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