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artemisinin-based combination therapy (ACT)

Phenotypic and genotypic characterization of Thai isolates of Plasmodium falciparum after an artemisinin resistance containment project

May 15, 2018 - 14:45 -- Open Access
Author(s): 
Thunyapit Thita, Pimrat Jadsri, Jarupatr Thamkhantho, Toon Ruang-areerate, Nantana Suwandittakul, Naruemon Sitthichot, Kittiya Mahotorn, Peerapan Tan-ariya and Mathirut Mungthin
Reference: 
Malaria Journal 2018 17:197, 15 May 2018

Although the containment project had been implemented in this area, the expansion of artemisinin-resistant parasites did not decline.

NOT Open Access | Emergence and Spread of kelch13 Mutations Associated with Artemisinin Resistance in Plasmodium falciparum Parasites in 12 Thai Provinces from 2007 to 2016

March 28, 2018 - 15:38 -- NOT Open Access
Author(s): 
Theerayot Kobasa, Eldin Talundzic, Nipon Chinanonwait, et al.
Reference: 
Antimicrob. Agents Chemother. April 2018 vol. 62 no. 4 e02141-17

Artemisinin-based combination therapy (ACT) is the most effective and widely used treatment for uncomplicated Plasmodium falciparum malaria and is a cornerstone for malaria control and prevention globally.

Efficacy and safety of artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Sudan: a systematic review and meta-analysis

March 15, 2018 - 06:56 -- Open Access
Author(s): 
Ishag Adam, Yassin Ibrahim and Gasim I. Gasim
Reference: 
Malaria Journal 2018 17:110, 13 March 2018

Based on this review, the overall malaria treatment success was high (98%). AL regimen showed higher efficacy compared to AS + SP.

The use and preference of artemether as a first-choice treatment for malaria: results from a cross-sectional survey in the Bata district, Equatorial Guinea

March 13, 2018 - 13:22 -- Open Access
Tags: 
Author(s): 
Maria Romay-Barja, Policarpo Ncogo, Agustin Benito, et al.
Reference: 
Malaria Journal 2018 17:107, 9 March 2018

Caregivers, public and private health staff, and drug sellers need to understand the importance of using ACT to treat uncomplicated malaria and the dangers of using artemisinin monotherapy.

Correlates of social behavior change communication on care-seeking behaviors for children with fever: an analysis of malaria household survey data from Liberia

March 7, 2018 - 16:12 -- Open Access
Tags: 
Author(s): 
Grace Awantang, Stella Babalola, Hannah Koenker, Kathleen Fox, Michael Toso, Nan Lewicky, Daniel Somah and Victor Koko
Reference: 
Malaria Journal 2018 17:105, 7 March 2018

Recalling the “Healthy Mother, Happy Baby” campaign was positively associated with the odds that children received ACT promptly, even in the absence of other malaria prevention and treatment messaging.

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The malaria testing and treatment landscape in Kenya: results from a nationally representative survey among the public and private sector in 2016

December 27, 2017 - 12:42 -- Open Access
Tags: 
Author(s): 
Anne Musuva, Waqo Ejersa, Rebecca Kiptui, Dorothy Memusi and Edward Abwao
Reference: 
Malaria Journal 2017 16:494, 21 December 2017

Although public sector availability of QAACT and malaria diagnosis is relatively high, there is a gap in availability of both testing and treatment that must be addressed.

Expanding malaria diagnosis and treatment in Lao PDR: lessons learned from a public–private mix initiative

November 15, 2017 - 16:03 -- Open Access
Author(s): 
Nouannipha Simmalavong, Sengkham Phommixay, Phoudaliphone Kongmanivong, Odai Sichanthongthip, Bouasy Hongvangthong, Deyer Gopinath and David M. Sintasath
Reference: 
Malaria Journal 2017 16:460, 13 November 2017

Ensuring adequate and timely supplies of RDTs and ACT to PPM sites is critical.

Challenges in implementing uncomplicated malaria treatment in children: a health facility survey in rural Malawi

November 5, 2017 - 18:39 -- Open Access
Tags: 
Author(s): 
Alinune N. Kabaghe, Mphatso D. Phiri, Kamija S. Phiri and Michèle van Vugt
Reference: 
Malaria Journal 2017 16:419, 18 October 2017

The survey presents an approach for assessing treatment effectiveness, highlighting bottlenecks which coverage indicators are incapable of detecting, and which may reduce quality and effectiveness of malaria treatment.

Person: 
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Social and cultural complexities of anti-malarial drug circulation: an ethnographic investigation in three rural remote communes of Cambodia

October 30, 2017 - 15:17 -- Open Access
Tags: 
Author(s): 
Phasy Res
Reference: 
Malaria Journal 2017 16:428, 25 October 2017

With a weak regulation system and ailing public health infrastructure, pharmaceutical-neoliberal mechanism like AMFm is not an effective means to eradicate any forms of malaria.

Malaria case management by community health workers in the Central African Republic from 2009–2014: overcoming challenges of access and instability due to conflict

October 3, 2017 - 17:22 -- Open Access
Tags: 
Author(s): 
Laura Ruckstuhl, Christian Lengeler, Jean Méthode Moyen, Helle Garro and Richard Allan
Reference: 
Malaria Journal 2017 16:388, 29 September 2017

Although the political crisis affected the CHWs, the programme showed that it could reach those most vulnerable and continue some level of care at all times.

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