All the tested ACT in mainland Tanzania were highly efficacious and none of validated k13 mutants associated with artemisinin resistance was observed.
artemisinin-based combination therapy (ACT)
All the anti-malarial drugs analysed in this study passed the quality control tests.
Haplotypes of P. falciparum in the western region of the Kingdom of Saudi Arabia exhibit high resistance against antifolate drugs.
The ASAQ combination remains highly effective for the treatment of uncomplicated falciparum malaria in Madagascar.
These findings confirm high efficacy of the first- and the newly recommended alternative ACT for treatments for uncomplicated falciparum malaria in Tanzania.
Both AS+SP and AS+MQ are safe and effective for treatment of uncomplicated falciparum malaria in pregnancy in India.
The longitudinal study showed a significant and relevant decline in the prevalence of P. falciparum infection after introduction of ACT, which could not be explained by potential confounders
The decline of malaria in Vietnam can largely be attributed to the adoption of artemisinin-based case management.
Although the containment project had been implemented in this area, the expansion of artemisinin-resistant parasites did not decline.
Artemisinin-based combination therapy (ACT) is the most effective and widely used treatment for uncomplicated Plasmodium falciparum malaria and is a cornerstone for malaria control and prevention globally.