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Solution behavior of hematin under acidic conditions and implications for its interactions with chloroquine

May 3, 2010 - 14:58 -- Patrick Sampao
Maria P. Crespo, Leann Tilley and Nectarios Klonis
Journal of Biological Inorganic Chemistry

The analysis reveals that aqua-ligated FP has a low propensity to self-associate and that the predominant self-associated species are homodimeric hydroxide-ligated FP and heterodimeric aqua/hydroxide-ligated FP.

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