Plasmodium parasites are the causative agents of malaria, a disease with wide public health repercussions. Increasing drug resistance and the absence of a vaccine make finding new chemotherapeutic strategies imperative.
Erythrocyte polymorphisms associated with a survival advantage to Plasmodium falciparum infection have undergone positive selection.
The ABO blood group influences susceptibility to severe Plasmodium falciparum malaria.
Malaria caused by Plasmodium falciparum results in approximately 1 million annual deaths worldwide, with young children and pregnant mothers at highest risk.
Chloroquine (CQ) was the best and most heavily used drug in the fight against malaria.
In this non-endemic setting, errors in RDT performance were mainly related to RDT test line interpretations, partly due to incorrect package insert instructions.