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DDT

Open Access | What drives community adherence to indoor residual spraying (IRS) against malaria in Manhica district, rural Mozambique: a qualitative study

November 24, 2011 - 09:16 -- Kabogo Ndegwa
Author(s): 
Munguambe K, Pool R, Montgomery C, Bavo C, Nhacolo A, Fiosse L, Sacoor C, Nhalungo D, Mabunda S, Macete E, Alonso P
Reference: 
Malaria Journal 2011, 10:344 (23 November 2011)

MalariaWorldThe study suggests that the contribution of IRS to malaria and mosquito control is not entirely perceived by the beneficiaries, and that other as cost effective interventions such as insecticide-treated nets are favoured over IRS.

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Open Access | Extensive permethrin and DDT resistance in Anopheles arabiensis from eastern and central Sudan

August 5, 2011 - 12:39 -- Patrick Sampao
Author(s): 
Yousif E Himeidan, Muzamil M Abdel Hamid, Christopher M Jones and Hilary Ranson
Reference: 
Parasites & Vectors 2011, 4:154

This study assessed resistance to permethrin and DDT in seven populations of Anopheles arabiensis from Sudan.

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The conspiracies behind malaria eradication in Africa must stop!

May 11, 2011 - 12:07 -- Stephen Yeboah

Malaria continues to threaten the lives of people despite huge funds made available to fight this preventable disease. According to the 2010 report “Breaking the Cycle: Saving Lives and Protecting the Future” by the Department for International Development (DFID), global funding for malaria has increased from $0.733 billion in 2006 to $1.94 billion in 2009. Despite the increasing funds for malaria control, the disease still kills about 800,000 people each year with the Africa [Sub-Saharan region] being the hardest hit [90 percent].

Glutathione S Transferase Activity in Indian Vectors of Malaria: A Defense Mechanism Against DDT

May 10, 2011 - 14:01 -- Patrick Sampao
Author(s): 
K. Gunasekaran, S. Muthukumaravel, S. S. Sahu, T. Vijayakumar, and P. Jambulingam
Reference: 
Journal of Medical Entomology 48(3):561-569. 2011

This investigation was to explore the metabolic status of GSTs in two Indian DDT-resistant malaria vectors, Anopheles culicifacies and Anopheles annularis, and one DDT-susceptible vector, Anopheles fluviatilis. Malkangiri and Koraput districts of Orissa State, endemic for falciparum malaria and having a long insecticide spraying history, were the study areas.

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Susceptibility of Anopheles gambiae s.l. to DDT, malathion, permethrin and deltamethrin in Ethiopia

March 17, 2011 - 08:56 -- Kabogo Ndegwa
Author(s): 
Alemayehu Abate and Mamuye Hadis
Reference: 
Tropical Medicine & International Health, Volume 16, Issue 4, pages 486–491, April 2011

The existence of high level of DDT and pyrethroid resistance with the possibility of cross-resistance to each other and other classes of agricultural pesticides could seriously jeopardise the efficacy of both ITNs and IRS in the country in the future.

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Open Access | Knockdown resistance (kdr)-like mutations in the voltage-gated sodium channel of a malaria vector Anopheles stephensi and PCR assays for their detection

March 15, 2011 - 08:43 -- Kabogo Ndegwa
Author(s): 
Singh OP, Dykes CL, Lather M, Agrawal OP, Adak T
Reference: 
Malaria Journal 2011, 10:59 (14 March 2011)

Two alternative kdr-like mutations, L1014S and L1014F, were detected in An. stephensi with a high allelic frequency of L1014S.

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Open Access | Some Lessons for the Future from the Global Malaria Eradication Programme (1955–1969)

January 27, 2011 - 10:05 -- Kabogo Ndegwa
Author(s): 
José A. Nájera, Matiana González-Silva, Pedro L. Alonso
Reference: 
PLoS Med 8(1): e1000412

Encouraged by the early success of using dichloro-diphenyl-trichloroethane (DDT) against malaria, the World Health Organization (WHO) embarked on the Global Malaria Eradication Program (GMEP) in 1955.

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Open Access | Correspondence: The Role of DDT in Malaria Control

July 8, 2010 - 07:52 -- Kabogo Ndegwa
Author(s): 
Hans Rudolf Herren, Charles Mbogo
Reference: 
Environ Health Perspect 118:a282-a282.

However well intentioned, Tren and Roberts (2010)—as with much of AFM’s output—do more to fuel those “interminable debates” than to meaningfully inform decisions that will save people’s lives.

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Spatio-Temporal Patterns in kdr Frequency in Permethrin and DDT Resistant Anopheles gambiae s.s. from Uganda

April 13, 2010 - 09:11 -- Patrick Sampao
Author(s): 
Katrijn Verhaeghen, Wim Van Bortel, Patricia Roelants, Paul Edward Okello, Ambrose Talisuna, AND Marc Coosemans
Reference: 
American Journal of Tropical Medicine Hygiene, Vol 82: 4, pp. 566-573

In the dry season, the kdr frequency was significantly higher in Plasmodium falciparum-infected mosquitoes, indicating that mosquitoes bearing a kdr mutation have a better adult survival, hence a higher likelihood of becoming infectious.

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