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lumefantrine bioavailability

Clinical Microbiology: The effect of food consumption on lumefantrine bioavailability in African children receiving artemether–lumefantrine crushed or dispersible tablets (Coartem®) for acute uncomplicated Plasmodium falciparum malaria

March 11, 2010 - 13:02 -- Patrick Sampao
Author(s): 
Steffen Borrmann, William M. Sallas, Steven E. Kern et al.
Reference: 
Tropical Medicine & International Health,Volume 15, Issue 4, April 2010

Concomitant food consumption may affect absorption of lumefantrine but data in the most important target population, i.e. children, are lacking. Therefore, we evaluated the effect of food intake on oral lumefantrine bioavailability in African children with malaria.

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