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HIV protease inhibitors

Antimalarial Asexual Stage-Specific and Gametocytocidal Activities of HIV Protease Inhibitors

February 25, 2010 - 21:41 -- Kabogo Ndegwa
Author(s): 
Christopher L. Peatey, Katherine T. Andrews, Nina Eickel, Timothy MacDonald, Alice S. Butterworth, Katharine R. Trenholme, Donald L. Gardiner, James S. McCarthy, and Tina S. Skinner-Adams
Reference: 
Antimicrobial Agents and Chemotherapy, March 2010, Pages 1334-1337, Volume. 54, No. 3

The stage-specific antimalarial activities of a panel of antiretroviral protease inhibitors (PIs), including two nonpeptidic PIs (tipranavir and darunavir), were tested in vitro against Plasmodium falciparum.

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