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drug-like non-piperidine

Open Access | Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols

February 17, 2010 - 20:15 -- Ingeborg van Schayk
Erin Milner, William McCalmont, Geoffrey Dow et al.
Malaria Journal 2010, 9:51 (11 February 2010)

Description of the in vitro screening of a library of mefloquine analogues, to find lead compounds that retain the favourable characteristics of mefloquine whilst minimizing the unfavourable ones of high BBB permeability. 

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