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Case Report: Transfusion-related Plasmodium ovale malaria complicated by acute respiratory distress syndrome (ARDS) in a non-endemic country

January 21, 2011 - 08:37 -- Patrick Sampao
Souha Haydoura, Ola Mazboudi, Khalil Charafeddine, Imad Bouakl, Tania A. Baban, Ali T. Taher, Souha S. Kanj
Parasitology International, Volume 60, Issue 1, January 2011, Pages 114-116

To our knowledge, this is the first case of acute respiratory distress syndrome (ARDS) secondary to blood transfusion related P. ovale malaria infection in a non-endemic country.

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Influence of haemoglobins S and C on predominantly asymptomatic Plasmodium infections in northern Ghana

October 22, 2010 - 09:46 -- Patrick Sampao
Ina Danquah, Peter Ziniel, Teunis A. Eggelte, Stephan Ehrhardt, Frank P. Mockenhaupt
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 104, Issue 11, November 2010, Pages 713-719

In this population with predominantly asymptomatic Plasmodium infection, HbAC shows no discernible effect on malaria-related parameters.


Association of Malaria-Induced Murine Pregnancy Failure with Robust Peripheral and Placental Cytokine Responses

October 25, 2009 - 16:36 -- Bart G.J. Knols
Jayakumar Poovassery and Julie M. Moore
Infect. Immun. 2009;77 4998-5006

Plasmodium chabaudi AS infection during early pregnancy results in midgestational embryonic loss in naive C57BL/6 mice. To define the immunopathogenesis of this malaria-induced pregnancy compromise, cytokine production in plasma, spleen, and placenta cell culture supernatants during the first 11 days of infection and gestation was studied. These results suggest that systemic and placenta-level proinflammatory antimalarial immune responses, in the absence of adequate and sustained counterregulatory mechanisms, contribute to pregnancy loss in this model.


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Current status of Plasmodium vivax vaccine

October 25, 2009 - 16:36 -- Ingeborg van Schayk
Myriam Arévalo-Herrera, Chetan Chitnis and Sócrates Herrera
Human Vaccines, Volume 6, Issue 1, January 2010

The increasing P. vivax drug resistance and reports of severe and lethal cases, the relapsing parasite behavior and the existence of Plasmodium spp co-infections must prompt more investment and greater efforts for the development of P. vivax vaccine.

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