Open Access | Lack of allele-specific efficacy of a bivalent AMA1 malaria vaccine
Reference:
Malaria Journal 2010, 9:175 (21 June 2010)
This Phase 2 trial of a bivalent AMA1 malaria vaccine found no evidence of vaccine selection or strain-specific efficacy, suggesting that the extreme genetic diversity of AMA1 did not account for failure of the vaccine to provide protection.
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