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rectal artesunate

Open Access | Understanding caretakers' dilemma in deciding whether or not to adhere with referral advice after pre-referral treatment with rectal artesunate

May 13, 2010 - 14:31 -- Kabogo Ndegwa
Simba DO, Kakoko DC, Warsame M, Premji Z, Gomes MF, Tomson G, Johansson E
Malaria Journal 2010, 9:123 (12 May 2010)

Successful implementation of the rectal artesunate strategy depends upon effective communication regarding referral to clinic.

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The use of placebo in a trial of rectal artesunate as initial treatment for severe malaria patients en route to referral clinics: ethical issues

February 15, 2010 - 12:14 -- Ingeborg van Schayk
Andrew Kitua, Peter Folb, Melba Gomes et al.
J. Med. Ethics. 2010; 36:116-120

Placebo-controlled trials are controversial when individuals might be denied existing beneficial medical interventions. In the case of malaria, most patients die in rural villages without healthcare facilities.

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