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cytotoxicity

In vitro antiplasmodial activity and cytotoxicity of nine plants traditionally used in Gabon

February 2, 2011 - 12:26 -- Patrick Sampao
Author(s): 
Jean Bernard Lekana-Douki., Jean Bernard Bongui., Maryvonne Kombila., et al.
Reference: 
Journal of Ethnopharmacology, Volume 133, Issue 3, 16 February 2011, Pages 1103-1108

As part of a project to identify new compounds active on malarial parasites, we tested the in vitro antiplasmodial activity of nine plants traditionally used to treat malaria symptoms in Haut-Ogooué Province, South-East Gabon.

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Antiplasmodial and cytotoxic activities of Rwandan medicinal plants used in the treatment of malaria

February 19, 2010 - 12:21 -- Kabogo Ndegwa
Author(s): 
Raymond Muganga, L. Angenot, M. Tits, M. Frédérich
Reference: 
Journal of Ethnopharmacology, Volume 128, Issue 1, 2 March 2010, Pages 52-57

The traditional use of most of the plant evaluated was confirmed by the antiplasmodial test. This study revealed for the first time the antiplasmodial activity of two plants: Terminalia mollis and Rumex abyssinicus.

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Synthesis, thermal stability, antimalarial activity of symmetrically and asymmetrically substituted tetraoxanes

February 13, 2010 - 11:49 -- Kabogo Ndegwa
Author(s): 
Himanshu Atheaya, Shabana I. Khan, Ritu Mamgain and Diwan S. Rawat
Reference: 
Bioorganic & Medicinal Chemistry Letters, Volume 18, Issue 4, 15 February 2008, Pages 1446-1449

Symmetrically and asymmetrically substituted 1,2,4,5-tetraoxanes were synthesized by the oxidative system H2O2/TFE in presence of MeReO3 as a catalyst.

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