A multiple dose, parallel group study was conducted to assess for a drug-drug interaction between the pyronaridine/artesunate (PA) combination antimalarial and ritonavir.
Am J Trop Med Hyg 2012 vol. 86 no. 3 489-495
British Journal of Clinical Pharmacology, Volume 69, Issue 3, March 2010, Pages: 262-270
Downward dosage adjustment of quinine appears necessary when concurrently administered with ritonavir.