The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10148 malaria professionals are enjoying the free benefits of MalariaWorld today

IPT

Prevalence of molecular markers of Plasmodium falciparum resistance to sulfadoxine–pyrimethamine during the intermittent preventive treatment in infants coupled with the expanded program immunization in Senegal

June 23, 2011 - 06:59 -- Kabogo Ndegwa
Author(s): 
Babacar Faye, Magatte Ndiaye, Oumar Gaye, et al.
Reference: 
Parasitology Research, Volume 109, Number 1, 133-138

Several studies have shown the efficacy of the intermittent preventive treatment (IPT) using sulfadoxine–pyrimethamine (SP) coupled with the expanded program of immunization (EPI) in infants.

Person: 
Country: 
Medical Condition: 
Medical Treatment: 

Induction of Antimalaria Immunity by Pyrimethamine Prophylaxis during Exposure to Sporozoites Is Curtailed by Parasite Resistance

May 24, 2011 - 07:47 -- Kabogo Ndegwa
Author(s): 
Johannes Friesen, Steffen Borrmann, and Kai Matuschewski
Reference: 
Antimicrobial Agents and Chemotherapy, June 2011,p. 2760-2767, Vol. 55, No. 6

Each year, infections with the protozoan parasite Plasmodium falciparum kill 1 million people, mostly children in Africa.

Medical Condition: 
Medical Treatment: 

Open Access | Evaluation of prevalences of pfdhfr and pfdhps mutations in Angola

February 9, 2011 - 07:46 -- Kabogo Ndegwa
Author(s): 
Fortes F, Dimbu R, Figueiredo P, Neto Z, do Rosario VE, Lopes D
Reference: 
Malaria Journal 2011, 10:22 (2 February 2011)

The data showed that the implementation IPT using SP in children needs to be reviewed.

Country: 
Medical Condition: 
Medical Treatment: 

Open Access | Intermittent preventive treatment of malaria with sulphadoxine-pyrimethamine during pregnancy in Burkina Faso: effect of adding a third dose to the standard two-dose regimen on low birth weight, anaemia and pregnancy outcomes

November 17, 2010 - 08:13 -- Kabogo Ndegwa
Author(s): 
Innocent Valea, Halidou Tinto, Maxime K Drabo, Lieven Huybregts, Marie-Claire Henry, Dominique Roberfroid, Robert T Guiguemde, Patrick Kolsteren, Umberto D'Alessandro, Micronutriments-Sante de la Mere et de l'Enfant MISAME/FSP study group
Reference: 
Malaria Journal 2010, 9:324 (12 November 2010)

The risk of LBW and severe anaemia tended to be lower in the SP3 group, though this was not statistically significant, probably due to the low uptake of the intervention which reduced the power of the study.

Country: 
Medical Condition: 
Medical Treatment: 

Open Access | Anti-bacterial activity of intermittent preventive treatment of malaria in pregnancy: comparative in vitro study of sulphadoxine-pyrimethamine, mefloquine, and azithromycin

November 3, 2010 - 08:09 -- Kabogo Ndegwa
Author(s): 
Capan M, Mombo-Ngoma G, Makristathis A, Ramharter M
Reference: 
Malaria Journal 2010, 9:303 (29 October 2010)

These data indicate important differences in the spectrum of anti-bacterial activity for the evaluated anti-malarial drugs.

Medical Condition: 

Open Access | Cost-Effectiveness of Intermittent Preventive Treatment of Malaria in Pregnancy in Southern Mozambique

October 22, 2010 - 10:12 -- Kabogo Ndegwa
Tags: 
Author(s): 
Elisa Sicuri, Azucena Bardají, Tacilta Nhampossa, Maria Maixenchs, Ariel Nhacolo, Delino Nhalungo, Pedro L. Alonso, Clara Menéndez
Reference: 
PLoS ONE 5(10): e13407

IPTp-SP was highly cost-effective for both prevention of maternal malaria and reduction of neonatal mortality in Mozambique. These findings are likely to hold for other settings where IPTp-SP is implemented through ANC visits.

Country: 
Medical Condition: 

Open Access | The Cost-Effectiveness of Intermittent Preventive Treatment for Malaria in Infants in Sub-Saharan Africa

June 18, 2010 - 10:37 -- Kabogo Ndegwa
Author(s): 
Lesong Conteh, Elisa Sicuri, Marcel Tanner, .et al
Reference: 
PLoS ONE 5(6): e10313

IPTi delivered alongside the EPI is a highly cost effective intervention against clinical malaria with a range of drugs in a range of malaria transmission settings. Where IPTi did not have a statistically significant impact on malaria, generally in low transmission sites, it was not cost effective.

Technology: 
Person: 
Medical Condition: 
Medical Treatment: 

Open Access | Therapeutics: Intermittent preventive treatment of infants with mefloquine reduces risk of clinical malaria in areas of moderate malaria transmission and high resistance to sulphadoxine-pyrimethamine

June 8, 2010 - 09:48 -- Kabogo Ndegwa
Author(s): 
R McGready
Reference: 
Evid Based Med (2010) 15: 71-2

Commentary on:

Gosling RD, Gesase S, Mosha JF, et al . Protective efficacy and safety of three antimalarial regimens for intermittent preventive treatment for malaria in infants: a randomised, double-blind, placebo-controlled trial. Lancet 2009;374:1521–32.

Person: 
Medical Condition: 

Antibodies to Chondroitin Sulfate A–Binding Infected Erythrocytes: Dynamics and Protection during Pregnancy in Women Receiving Intermittent Preventive Treatment

April 9, 2010 - 17:46 -- Ingeborg van Schayk
Author(s): 
Elizabeth H. Aitken, Bernard Mbewe, Mari Luntamo, Ken Maleta, Teija Kulmala, Marc‐James Friso, Freya J. I. Fowkes, James G. Beeson, Per Ashorn, and Stephen J. Rogerson
Reference: 
The Journal of Infectious Diseases 2010;201:1316–1325

Levels of IgG antibody to pregnancy‐specific VSAs decrease during receipt of IPTp. Antibody levels in early pregnancy did not predict clinical outcome. IPTp and decreasing malaria prevalence pose challenges for the evaluation of novel interventions for malaria during pregnancy.

Medical Treatment: 

Open Access | Intermittent preventive treatment in infants for the prevention of malaria in rural Western Kenya: a randomized, double-blind placebo-controlled trial

April 8, 2010 - 07:00 -- Kabogo Ndegwa
Author(s): 
FO Odhiambo, MJ Hamel, J Williamson, K Lindblade, FO ter Kuile, E Peterson, P Otieno, S Kariuki, J Vulule, L Slutsker, RD Newman
Reference: 
PLoS One (2010) 5: e10016.

IPTi with long-acting regimens provide protection against clinical malaria for up to 8 weeks even in the presence of high ITN coverage, and that the prophylactic rather than the treatment effect of IPTi appears central to its protective efficacy.

Technology: 
Person: 
Country: 
Medical Condition: 
Medical Treatment: 

Pages

Subscribe to RSS - IPT