To develop a new animal model for MA-ARDS, mice were infected with Plasmodium berghei NK65, and the development of MA-ARDS was characterized by increased lung weight, edema, leukocyte infiltration and hemorrhages (Figure 1).
Malaria Journal 2010, 9(Suppl 2):I13 (20 October 2010)
Am. J. Respir. Crit. Care Med. 2010, Published ahead of print on January 21, 2010
The finding that high doses of dexamethasone cured MA-ARDS suggests that it might be more effective against MA-ARDS than it was in the clinical trials for cerebral malaria.