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Open Access | Insecticide-treated net (ITN) ownership, usage, and malaria transmission in the highlands of western Kenya

June 20, 2011 - 14:16 -- Patrick Sampao
Author(s): 
Harrysone E Atieli, Guofa Zhou, Yaw A Afrane, Ming-Chieh Lee, Isaac Mwanzo, Andrew K Githeko and Guiyun Yan
Reference: 
Parasites & Vectors 2011, 4:11 , 18 June 2011

This study examined ITN ownership and underlying factors for among-household variation in use, and malaria transmission in two highland regions of western Kenya.

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Epidemiology and Infectivity of Plasmodium falciparum and Plasmodium vivax Gametocytes in Relation to Malaria Control and Elimination

April 12, 2011 - 14:15 -- Patrick Sampao
Author(s): 
Teun Bousema and Chris Drakeley
Reference: 
Clin. Microbiol. Rev., Apr 2011; 24: 377 - 410.

We discuss how the application of molecular techniques has led to the identification of submicroscopic gametocyte carriage and to a reassessment of the human infectious reservoir.

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Open Access | NSR-seq transcriptional profiling enables identification of a gene signature of Plasmodium falciparum parasites infecting children

February 22, 2011 - 07:38 -- Kabogo Ndegwa
Author(s): 
M Vignali, CD Armour, J Chen, R Morrison, JC Castle, MC Biery, H Bouzek, W Moon, T Babak, M Fried, CK Raymond, PE Duffy
Reference: 
Journal of Clinical Investigation

Malaria caused by Plasmodium falciparum results in approximately 1 million annual deaths worldwide, with young children and pregnant mothers at highest risk.

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Experts in favour of tighter rules for DDT use against malaria

February 2, 2011 - 08:48 -- Guest (not verified)

UN-Experts on DDT recommend stricter rules when DDT is used for malaria vector control. Their report published ahead of the 5th Conference of the Parties to the Stockholm Convention (COP-5, Geneva April 25-29, 2011), shows more and more concern about effects of DDT on human health as well as on the environment. Their report was released last week, showing that the international community might be moving towards new rules on the use of DDT.

Case Report: Transfusion-related Plasmodium ovale malaria complicated by acute respiratory distress syndrome (ARDS) in a non-endemic country

January 21, 2011 - 08:37 -- Patrick Sampao
Author(s): 
Souha Haydoura, Ola Mazboudi, Khalil Charafeddine, Imad Bouakl, Tania A. Baban, Ali T. Taher, Souha S. Kanj
Reference: 
Parasitology International, Volume 60, Issue 1, January 2011, Pages 114-116

To our knowledge, this is the first case of acute respiratory distress syndrome (ARDS) secondary to blood transfusion related P. ovale malaria infection in a non-endemic country.

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Open Access | Oral Presentation: Molecular epidemiology of force of infection in malaria

November 8, 2010 - 08:56 -- Patrick Sampao
Author(s): 
Ingrid Felger, Sonja Schoepflin, Benson Kiniboro, Peter A Zimmerman, Ivo Mueller
Reference: 
Malaria Journal 2010, 9(Suppl 2):O14 (20 October 2010)

We investigated the ability of molecular parameters to explain differences in the risk of P. falciparum infection and disease between wet and dry seasons, among age groups and with respect to insecticide-treated mosquito net use.

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Open Access | Transmission Intensity and Drug Resistance in Malaria Population Dynamics: Implications for Climate Change

October 30, 2010 - 12:39 -- Kabogo Ndegwa
Author(s): 
Yael Artzy-Randrup, David Alonso, Mercedes Pascual
Reference: 
PLoS ONE 5(10): e13588

Although the spread of drug resistance and the influence of climate change on malaria are most often considered separately, these factors have the potential to interact through altered levels of transmission intensity.

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Parasitology: PCR-Based Pooling of Dried Blood Spots for Detection of Malaria Parasites: Optimization and Application to a Cohort of Ugandan Children

October 1, 2010 - 08:57 -- Patrick Sampao
Author(s): 
Michelle S. Hsiang, Michael Lin, Christian Dokomajilar, Jordan Kemere, Christopher D. Pilcher, Grant Dorsey, and Bryan Greenhouse
Reference: 
J. Clin. Microbiol., Oct 2010; 48: 3539 - 3543.

We first used laboratory-prepared samples to compare 2 DNA extraction and 4 PCR detection methods across a range of pool sizes and parasite densities. Pooled Chelex extraction of DNA, followed by nested PCR of cytochrome b, was the optimal strategy, allowing reliable detection of a single low-parasitemic sample (100 parasites/µl) in pool sizes up to 50.

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Open Access | Availability and utilization of malaria prevention strategies in pregnancy in eastern India

September 20, 2010 - 14:38 -- Patrick Sampao
Author(s): 
Wylie BJ., Hashmi AH., et al.
Reference: 
BMC Public Health 2010, 10:557 (17 September 2010)

This cross-sectional study was conducted during 2006-2008 in two states of India, Jharkhand and Chhattisgarh, at 7 facilities representing a range of rural and urban populations and areas of more versus less stable malaria transmission.

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Seminar: Malaria in children

April 26, 2010 - 14:02 -- Patrick Sampao
Author(s): 
Jane Crawley, Cindy Chu, George Mtove, François Nosten
Reference: 
The Lancet, Volume 375, Issue 9724, 24 April 2010-30 April 2010, Pages 1468-1481

This Seminar, which is aimed at clinicians who manage children with malaria,especially in resource-poor settings, discusses present knowledge and controversies in relation to the epidemiology, pathophysiology, diagnosis, treatment, and prevention of malaria in children.

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