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quinazoline

Synthesis and antiplasmodial activity of new 4-aryl-2-trichloromethylquinazolines

December 22, 2009 - 13:19 -- Patrick Sampao
Author(s): 
Pierre Verhaeghe, Nadine Azas, Monique Gasquet, Sébastien Hutter, Christophe Ducros, Michèle Laget, Sylvain Rault, Pascal Rathelot, Patrice Vanelle
Reference: 
Bioorganic & Medicinal Chemistry Letters, Volume 18, Issue 1, 1 January 2008, Pages 396-401

A series of original 4-aryl-substituted 2-trichloromethylquinazoline derivatives was synthesized using a microwave-assisted Suzuki-Miyaura cross-coupling approach.

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