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diaminopyrimidines

Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines

December 22, 2009 - 12:41 -- Patrick Sampao
Author(s): 
Derek C. Martyn, Amarjit Nijjar, Cassandra A. Celatka, Ralph Mazitschek, Joseph F. Cortese, Erin Tyndall, Hanlan Liu, Maria M. Fitzgerald, Thomas J. O’Shea, Sanjay Danthi, Jon Clardy
Reference: 
Bioorganic & Medicinal Chemistry Letters, Volume 20, Issue 1, 1 January 2010, Pages 228-231

Two sets of diaminopyrimidines, totalling 45 compounds, were synthesized and assayed against Plasmodium falciparum.

Medical Condition: 
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