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artesunate mefloquine

A Randomized Trial of Artesunate Mefloquine versus Artemether Lumefantrine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in Senegalese Children

January 14, 2010 - 10:55 -- Ingeborg van Schayk
Author(s): 
Babacar Faye, Jean Louis Ndiaye, Roger Tine, Khadim Sylla, Ali Gueye, Aminata Colle Lô, AND Oumar Gaye
Reference: 
Am J Trop Med Hyg 2010;82 140-144

An open randomized clinical trial study was carried out to compare efficacy and tolerability of artesunate mefloquine 25 mg/kg body weight (Artequin paediatric) versus artemether lumefantrine (Coartem) in the treatment of uncomplicated Plasmodium falciparum malaria in children.

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Open Access | Effects of mefloquine and artesunate mefloquine on the emergence, clearance and sex ratio of Plasmodium falciparum gametocytes in malarious children

December 23, 2009 - 11:35 -- Ingeborg van Schayk
Author(s): 
Akintunde Sowunmi, Oluchi O Nkogho, Titilope M Okuboyejo, Grace O Gbotosho, Christian T Happi, Elsie O Adewoye
Reference: 
Malaria Journal 2009, 8:297 (16 December 2009)

Addition of artesunate to mefloquine significantly modified the emergence, clearance, and densities of gametocytes and has short-lived, but significant, sex ratio modifying effects in children from this endemic area.

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