The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 11024 malaria professionals are enjoying the free benefits of MalariaWorld today

high antibody titer

Open Access | High Antibody Titer against Apical Membrane Antigen-1 Is Required to Protect against Malaria in the Aotus Model

December 22, 2009 - 11:48 -- Ingeborg van Schayk
Dutta S, Sullivan JS, Grady KK, Haynes JD, Komisar J, et al.
PLoS ONE 4(12): e8138

A Plasmodium falciparum 3D7 strain Apical Membrane Antigen-1 (AMA1) vaccine, formulated with AS02A adjuvant, slowed parasite growth in a recent Phase 1/2a trial, however sterile protection was not observed. We tested this AS02A, and a Montanide ISA720 (ISA) formulation of 3D7 AMA1 in Aotus monkeys.

Medical Condition: 
Medical Treatment: 
Subscribe to RSS - high antibody titer