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halofantrine

Open Access | Effects of anti-malarial drugs on the electrocardiographic QT interval modelled in the isolated perfused guinea pig heart system

November 16, 2010 - 13:13 -- Kabogo Ndegwa
Author(s): 
Atsushi Kinoshita, Harumi Yamada, Hajime Kotaki, Mikio Kimura
Reference: 
Malaria Journal 2010, 9:318 (10 November 2010)

In this study, an isolated, perfused guinea pig heart system was constructed to assess the cardiotoxic potential of anti-malarial drugs.

Open Access | Fatal cardiotoxicity related to halofantrine: a review based on a worldwide safety data base

December 14, 2009 - 13:43 -- Ingeborg van Schayk
Tags: 
Author(s): 
Olivier Bouchaud, Patrick Imbert, Jean-Etienne Touze, Alex NO Dodoo, Martin Danis, Fabrice Legros
Reference: 
Malaria Journal 2009, 8:289 (10 December 2009)

Halofantrine (HF) was considered an effective and safe treatment for multi-drug resistant falciparum malaria until 1993, when the first case of drug-associated death was reported.

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