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anti malarial agents

Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents

June 11, 2019 - 15:02 -- Open Access
Barbara H. Stokes, Euna Yoo, David A. Fidock, et al.
PLoS Pathog 15(6): e1007722

Therapeutics with novel modes of action and a low risk of generating resistance are urgently needed to combat drug-resistant Plasmodium falciparum malaria.

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