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intermittent preventive treatment of malaria in pregnancy (IPTp)

NOT Open Access | Population Pharmacokinetics of Mefloquine Intermittent Preventive Treatment for Malaria in Pregnancy in Gabon

February 6, 2019 - 15:24 -- NOT Open Access
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Author(s): 
Michael Ramharter, Matthias Schwab, Thorsten Lehr, et al.
Reference: 
Antimicrob. Agents Chemother. January 2019 63:e01113-18

Mefloquine was evaluated as an alternative for intermittent preventive treatment of malaria in pregnancy (IPTp) due to increasing resistance against the first-line drug sulfadoxine-pyrimethamine (SP).

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A decade since sulfonamide-based anti-malarial medicines were limited for intermittent preventive treatment of malaria among pregnant women in Tanzania

November 7, 2018 - 15:01 -- Open Access
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Author(s): 
Alphonce I. Marealle, Dennis P. Mbwambo, Wigilya P. Mikomangwa, Manase Kilonzi, Hamu J. Mlyuka and Ritah F. Mutagonda
Reference: 
Malaria Journal 2018 17:409, 6 November 2018

Majority of the medicine dispensers in the community pharmaceutical outlets were knowledgeable about SPs and their indications.

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Dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria during pregnancy and risk of malaria in early childhood: A randomized controlled trial

July 19, 2018 - 16:42 -- Open Access
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Author(s): 
Prasanna Jagannathan, Abel Kakuru, Grant Dorsey, et al.
Reference: 
PLoS Med 15(7): e1002606

 

Contrary to our hypothesis, preventing malaria in pregnancy with IPTp-DP in the context of chemoprevention with DP during infancy does not lead to a reduced incidence of malaria in childhood; in this setting, it may be associated with an increased incidence of malaria in females. F

Mortality, Morbidity, and Developmental Outcomes in Infants Born to Women Who Received Either Mefloquine or Sulfadoxine-Pyrimethamine as Intermittent Preventive Treatment of Malaria in Pregnancy: A Cohort Study

March 3, 2016 - 14:50 -- Open Access
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Author(s): 
María Rupérez, Raquel González, Clara Menéndez, et al.
Reference: 
PLoS Med 13(2): e1001964

No significant differences were found between IPTp with MQ and SP administered in pregnancy on infant mortality, morbidity, and nutritional outcomes.

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