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anti-malarial drugs

Open Access | A progressive declining in the burden of malaria in north-eastern Tanzania

July 27, 2010 - 13:50 -- Kabogo Ndegwa
Author(s): 
Mmbando BP, Vestergaard LS, Kitua AY, Lemnge MM, Theander TG, Lusingu JP
Reference: 
Malaria Journal 2010, 9:216 (23 July 2010)

There has been a marked decline in malaria in the study villages during the past few years. This decline is likely to be due to a combination of factors that include improved access to malaria treatment provided by the trained village helpers, protection from mosquitoes by increased availability of insecticide-impregnated bed nets and a reduced vector density.

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Open Access | Progress and challenges to control malaria in a remote area of Chittagong hill tracts, Bangladesh

June 11, 2010 - 09:05 -- Kabogo Ndegwa
Author(s): 
Haque U, Hashizume M, Sunahara T, Hossain S, Masud Ahmed S, Haque R, Yamamoto T, Glass GE
Reference: 
Malaria Journal 2010, 9:156 (10 June 2010)

Closeness to health facilities runs by the malaria control programme and drug vendors were significantly associated with the choice of treatment. A high proportion of people preferred drug vendors without having a proper diagnosis.

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Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate

January 21, 2010 - 09:13 -- Kabogo Ndegwa
Author(s): 
Wanna Chaijaroenkula, Raewadee Wisedpanichkija and Kesara Na-Bangchang
Reference: 
Acta Tropica, Volume 113, Issue 2, February 2010, Pages 190-194

The objective of this work was to broaden the insight into the molecular mechanisms of resistance of P. falciparum to quinoline-containing antimalarials and artemisinin derivatives.

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Open Access | Plasmodium falciparum resistance to anti-malarial drugs in Papua New Guinea: evaluation of a community-based approach for the molecular monitoring of resistance

January 13, 2010 - 13:15 -- Ingeborg van Schayk
Author(s): 
Jutta Marfurt, Thomas A Smith, Ian M Hastings, Ivo Muller, Albert Sie, Olive Oa, Moses Baisor, John C Reeder, Hans-Peter Beck, Blaise Genton
Reference: 
Malaria Journal 2010, 9:8 (7 January 2010)

Interesting paper aiming at investigating the role and applicability of the molecular drug resistance profiles in community samples in Papua New Guinea.

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Open Access | A microarray-based system for the simultaneous analysis of single nucleotide polymorphisms in human genes involved in the metabolism of anti-malarial drugs

December 14, 2009 - 11:45 -- Ingeborg van Schayk
Author(s): 
Eva-Maria Hodel, Serej D Ley, Weihong Qi, Frederic Ariey, Blaise Genton, Hans-Peter Beck
Reference: 
Malaria Journal 2009, 8:285 (9 December 2009)

The major limit of the microarray technology for this purpose was lack of robustness and with a large number of missing data or with incorrect specificity.

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Open Access | Methodology: Haemoglobin interference and increased sensitivity of fluorimetric assays for quantification of low-parasitaemia Plasmodium infected erythrocytes

December 14, 2009 - 11:07 -- Ingeborg van Schayk
Author(s): 
Carlos Moneriz, Patricica Marin-Garcia, Jose M Bautista, Amalia Diez, Antonio Puyet
Reference: 
Malaria Journal 2009, 8:279 (4 December 2009)

The use of PG microassays on detergent-free, haemoglobin-depleted samples appears as the best choice both for the detection of Plasmodium in low-density infections and anti-malarial drugs tests.

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