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primaquine (PQ)

Safety of primaquine in infants with Plasmodium vivax malaria in Papua, Indonesia

April 4, 2019 - 15:51 -- Open Access
Author(s): 
Agus Setyadi, Eggi Arguni, Jeanne R. Poespoprodjo, et al.
Reference: 
Malaria Journal 2019 18:111, 2 April 2019

Severe clinical outcomes amongst infants treated with primaquine in Papua were rare.

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Factors associated with children’s health facility visits for primaquine treatment in rural Papua New Guinea

February 21, 2019 - 16:30 -- Open Access
Author(s): 
Akiko Yoshii, Makoto Sekihara, Takuro Furusawa, Francis Hombhanje and Takahiro Tsukahara
Reference: 
Malaria Journal 2019 18:42, 20 February 2019

Few children received PQ treatment during the second visit to HFs following diagnosis of potential non-falciparum malaria.

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Quantifying primaquine effectiveness and improving adherence: a round table discussion of the APMEN Vivax Working Group

June 26, 2018 - 16:24 -- Open Access
Tags: 
Author(s): 
Kamala Thriemer, Albino Bobogare, Ric N. Price, et al.
Reference: 
Malaria Journal 2018 17:241, 20 June 2018

The goal to eliminate malaria from the Asia-Pacific by 2030 will require the safe and widespread delivery of effective radical cure of malaria.

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Understanding human genetic factors influencing primaquine safety and efficacy to guide primaquine roll-out in a pre-elimination setting in southern Africa

March 27, 2018 - 15:33 -- Open Access
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Author(s): 
Shehu S. Awandu, Jaishree Raman, Takalani I. Makhanthisa, Philip Kruger, John Frean, Teun Bousema, Jandeli Niemand and Lyn-Marie Birkholtz
Reference: 
Malaria Journal 2018 17:120, 20 March 2018

Phenotypic and genotypic analyses both detected low prevalence of G6PD deficiency and the CYP2D6*4 variants.

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NOT Open Access | Synthesis, characterization, and cellular localization of a fluorescent probe of the antimalarial 8-aminoquinoline primaquine

October 12, 2017 - 15:26 -- NOT Open Access
Author(s): 
Adonis McQueen, Lynn D. Blake, Dennis E. Kyle, et al.
Reference: 
Bioorganic & Medicinal Chemistry Letters, Volume 27, Issue 20, 15 October 2017, Pages 4597-4600

Primaquine (PQ) is the only commercially available drug that clears dormant liver stages of malaria and blocks transmission to mosquito vectors.

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Effectiveness of combined chloroquine and primaquine treatment in 14 days versus intermittent single dose regimen, in an open, non-randomized, clinical trial, to eliminate Plasmodium vivax in southern Mexico

November 4, 2015 - 13:34 -- Open Access
Author(s): 
Lilia Gonzalez-Ceron, Mario Rodriguez, Marco Sandoval, Frida Santillan, Sonia Galindo-Virgen, Angel Betanzos, Angel Rosales, Olga Palomeque
Reference: 
Malaria Journal 2015, 14:426 (30 October 2015)

T14 was effective for opportune elimination of the primary blood infection and preventing relapse episodes.

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