AL, ASAQ, and DP continue to be efficacious against P. falciparum malaria in these provinces of Angola.
Whilst AN has superior overall efficacy for the treatment of uncomplicated malaria in PNG children, AL was the less costly regimen.
Public sector outlets in the southern Lao PDR are typically equipped to test and appropriately treat malaria.
Malian post-AL P. falciparum isolates were less susceptible to artemether and lumefantrine than baseline isolates.
In this efficacy trial, SMS reminders increased post-treatment return to the health facility, but had no effect on AL adherence which was high in both control and intervention groups.
ASAQ is still effective as a treatment for uncomplicated malaria in Baraka, South Kivu, DRC.
Although treatment is highly efficacious, selection of molecular markers in reinfections could indicate a decreased sensitivity or tolerance of parasites to the current treatments and the baseline prevalence of molecular markers should be closely monitored.
The relatively high cure rate, low proportion of patients still positive on day 3 as well as parasite clearance times in this study would indicate no imminent threat of artemisinin resistance development in the region.