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artemisinin-based combinations

High cure rates and tolerability of artesunate–amodiaquine and dihydroartemisinin–piperaquine for the treatment of uncomplicated falciparum malaria in Kibaha and Kigoma, Tanzania

March 27, 2019 - 15:59 -- Open Access
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Author(s): 
Celine I. Mandara, Filbert Francis, Deus S. Ishengoma, et al.
Reference: 
Malaria Journal 2019 18:99, 25 March 2019

Both artemisinin-based combinations had high cure rates with PCR corrected ACPR of 100%.

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Efficacy and safety of artemisinin-based combination therapy and chloroquine with concomitant primaquine to treat Plasmodium vivax malaria in Brazil: an open label randomized clinical trial

January 24, 2018 - 13:30 -- Open Access
Author(s): 
André Daher, Dhelio Pereira, David G. Lalloo, et al.
Reference: 
Malaria Journal 2018 17:45, 24 January 2018

This study demonstrated the efficacy and safety of all three regimens that were tested with 42-day cure rates that meet World Health Organization criteria.

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Ex vivo anti-malarial drug susceptibility of Plasmodium falciparum isolates from pregnant women in an area of highly seasonal transmission in Burkina Faso

June 20, 2015 - 10:17 -- Open Access
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Author(s): 
Marc C Tahita, Halidou Tinto, Umberto D’Alessandro, et al.
Reference: 
Malaria Journal 2015, 14:251 (20 June 2015)

These ex vivo results suggest that treatment with the currently available artemisinin-based combinations is efficacious for the treatment of malaria in pregnancy in Burkina Faso.

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