Where universal coverage targets for LLIN utilization has been achieved, supplementing LLINs with IRS using pyrethroids may reduce malaria transmission below levels achieved by LLIN use alone, even in settings where pyrethroid resistance occurs in the vector population.
insecticidal nets (LLINs)
Malaria Journal 2016 15:100, 18 February 2016
Malaria Journal 2013, 12:215 (26 June 2013)
Shifts towards crepuscular host searching behaviour can be as important in reducing LLIN effectiveness and cost effectiveness as resistance to pyrethroids.