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long-lasting insecticide-treated nets (LLINs)

A qualitative study on the use of long-lasting insecticidal nets (LLINs) for the prevention of malaria in the Peruvian Amazon

September 10, 2019 - 15:21 -- Open Access
Author(s): 
Mia Iyer, John Skelton, Giles de Wildt and Graziela Meza
Reference: 
Malar Journal 2019 18:301, 2 September 2019

Malaria is a huge global health burden due to its mortality, morbidity and cost to economies. It is necessary to eliminate the disease in all countries where possible to achieve the World Health Organization target of > 90% reduction by 2030. Successful previous campaigns suggest elimination is feasible in Peru. However, the incidence has recently been rising, focalized to the region of Loreto. Currently, the distribution of long-lasting insecticide-treated nets (LLINs) is a major part of Peru’s malaria control strategy, however these may be having a limited effect in Loreto, because of the recent behavioural adaption of the mosquito vector, Anopheles darlingi, to earlier biting times, as well as local perceptions and practices towards LLINs. It was, therefore, necessary to investigate how perceptions, practices and lifestyle factors affect the efficacy of LLINs in Loreto.

Synergy and timing: a concurrent mass medical campaign predicted to augment indoor residual spraying for malaria

May 7, 2019 - 13:54 -- Open Access
Author(s): 
Richard C. Elliott, David L. Smith and Dorothy C. Echodu
Reference: 
Malaria Journal 2019 18:160, 6 May 2019

Control programmes for high burden countries are tasked with charting effective multi-year strategies for malaria control within significant resource constraints. Synergies between different control tools, in which more than additive benefit accrues from interventions used together, are of interest because they may be used to obtain savings or to maximize health impact per expenditure. One commonly used intervention in sub-Saharan Africa is indoor residual spraying (IRS), typically deployed through a mass campaign. While possible synergies between IRS and long-lasting insecticide-treated nets (LLINs) have been investigated in multiple transmission settings, coordinated synergy between IRS and other mass medical distribution campaigns have not attracted much attention. Recently, a strong timing-dependent synergy between an IRS campaign and a mass drug administration (MDA) was theoretically quantified. These synergistic benefits likely differ across settings depending on transmission intensity and its overall seasonal pattern.

Evaluation of a push–pull system consisting of transfluthrin-treated eave ribbons and odour-baited traps for control of indoor- and outdoor-biting malaria vectors

March 20, 2019 - 16:09 -- Open Access
Author(s): 
Arnold S. Mmbando, Elis P. A. Batista, Fredros O. Okumu, et al.
Reference: 
Malaria Journal 2019 18:87, 20 March 2019

The best configuration of push–pull comprised transfluthrin-treated eave ribbons plus two traps, each at least 15 m from huts.

Mosquito repellents for malaria prevention

July 3, 2018 - 16:19 -- Open Access
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Author(s): 
Marta F Maia, Merav Kliner, Marty Richardson, Christian Lengeler, Sarah J Moore
Reference: 
Cochrane Infectious Diseases Group, 6 February 2018

Two review authors independently reviewed trials for inclusion, extracted the data, and assessed the risk of bias.

Investigating insecticide resistance and knock-down resistance (kdr) mutation in Dielmo, Senegal, an area under long lasting insecticidal-treated nets universal coverage for 10 years

March 27, 2018 - 15:38 -- Open Access
Author(s): 
Omar Thiaw, Souleymane Doucouré, Seynabou Sougoufara, Charles Bouganali, Lassana Konaté, Nafissatou Diagne, Ousmane Faye and Cheikh Sokhna
Reference: 
Malaria Journal 2018 17:123, 22 March 2018

The co-occurrence of 1014F and 1014S alleles and the probable involvement of GSTs enzymes in insecticide resistance in An. gambiae s.l. should prompt the local vector programme to implement non-pyrethroid/DDT insecticides alternatives.

The paradigm of eave tubes: scaling up house improvement and optimizing insecticide delivery against disease-transmitting mosquitoes

May 25, 2017 - 06:01 -- Open Access
Author(s): 
Fredros Okumu
Reference: 
Malaria Journal 2017 16:207, 19 May 2017

Control of mosquito-borne diseases is greatly compromised by spread of insecticide resistance, high implementation costs and sub-optimal compliance among users.

Malaria transmission dynamics surrounding the first nationwide long-lasting insecticidal net distribution in Papua New Guinea

January 12, 2016 - 17:28 -- Open Access
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Author(s): 
Lisa Reimer, Edward Thomsen, Gussy Koimbu, John Keven, Ivo Mueller, Peter Siba, James Kazura, Manuel Hetzel, Peter Zimmerman
Reference: 
Malaria Journal 2016, 15:25 (12 January 2016)

LLINs had a significant impact on malaria transmission, despite exophagic and crepuscular feeding behaviours of dominant vectors.

Bio-efficacy of new long-lasting insecticide-treated bed nets against Anopheles funestus and Anopheles gambiae from central and northern Mozambique

September 22, 2015 - 17:45 -- Open Access
Author(s): 
Ana Abílio, Pelágio Marrune, Nilsa de Deus, Francisco Mbofana, Pedro Muianga, Ayubo Kampango
Reference: 
Malaria Journal 2015, 14:352 (17 September 2015)

The study shows evidence of considerable heterogeneity in both insecticide susceptibility and the level of bio-efficacy of commonly available types of LLINs against wild A. funestus and A. gambiae from Balama, Mocuba and Milange districts, located in north and centre of Mozambique.

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Transmission and Control of Plasmodium knowlesi: A Mathematical Modelling Study

July 30, 2014 - 06:36 -- Open Access
Author(s): 
Natsuko Imai, Michael T. White, Azra C. Ghani, Chris J. Drakeley
Reference: 
PLoS Negl Trop Dis 8(7): e2978

This model simulates conditions where P. knowlesi transmission may occur and the potential impact of control measures.

High level of resistance in the mosquito Anopheles gambiae to pyrethroid insecticides and reduced susceptibility to bendiocarb in north-western Tanzania

May 7, 2013 - 09:22 -- Open Access
Author(s): 
Protopopoff N, Matowo J, Malima R, Kavishe R, Kaaya R, Wright A, West PA, Kleinschmidt I, Kisinza W, Mosha FW, Rowland M
Reference: 
Malaria Journal 2013, 12:149 (2 May 2013)
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Anopheles gambiae s.s has developed phenotypic resistance to pyrethroids and DDT and kdr frequency has almost reached fixation.

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