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Rapid diagnostic tests (RDT)

High proportions of pfhrp2 gene deletion and performance of HRP2-based rapid diagnostic test in Plasmodium falciparum field isolates of Odisha

October 31, 2018 - 15:23 -- Open Access
Author(s): 
Pallabi Pati, Gunanidhi Dhangadamajhi, Madhusmita Bal and Manoranjan Ranjit
Reference: 
Malaria Journal 2018 17:394, 29 October 2018

High prevalence of parasites with pfhrp2 deletion including dual deletions (pfhrp2 and pfhrp3) is a serious cause of concern, as these patients could not be given a correct diagnosis and treatment.

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The impact of the scale-up of malaria rapid diagnostic tests on the routine clinical diagnosis procedures for febrile illness: a series of repeated cross-sectional studies in Papua New Guinea

May 17, 2018 - 15:32 -- Open Access
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Author(s): 
Justin Pulford, Serah Kurumop, Ivo Mueller, Peter M. Siba and Manuel W. Hetzel
Reference: 
Malaria Journal 2018 17:202, 16 May 2018

Rapid diagnostic tests scale-up has led to a reduction in body temperature measurement. Investigations are very limited when malaria infection is ruled out as a cause of febrile illness by RDT.

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Provider and patient perceptions of malaria rapid diagnostic test use in Nigeria: a cross-sectional evaluation

May 17, 2018 - 15:30 -- Open Access
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Author(s): 
Olugbenga A. Mokuolu, Olufemi O. Ajumobi, Bala M. Audu, et al.
Reference: 
Malaria Journal 2018 17:200, 16 May 2018

The study demonstrated positive perception to RDT use by HW and among community members with good compliance rate among health workers at the PHC level.

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Performance of an ultra-sensitive Plasmodium falciparum HRP2-based rapid diagnostic test with recombinant HRP2, culture parasites, and archived whole blood samples

March 20, 2018 - 14:24 -- Open Access
Author(s): 
Smita Das, Roger B. Peck, Rebecca Barney, Ihn Kyung Jang, Maria Kahn, Meilin Zhu and Gonzalo J. Domingo
Reference: 
Malaria Journal 2018 17:118, 17 March 2018

The performance of the uRDT was variable depending on the protein, but overall showed a greater than 10-fold improvement over the SD-RDT.

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Self-diagnosis of malaria by travellers: a cohort study on the use of malaria rapid diagnostic tests provided by a Swiss travel clinic

October 30, 2017 - 15:25 -- Open Access
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Author(s): 
Delphine Berthod, Jacynthe Rochat, Rachel Voumard, Laurence Rochat, Blaise Genton and Valérie D’Acremont
Reference: 
Malaria Journal 2017 16:436, 28 October 2017

1/6 travellers experienced fever and 4/5 of those reacted appropriately: more than half used RDTs and a quarter consulted immediately.

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Evidence of non-Plasmodium falciparum malaria infection in Kédougou, Sénégal

January 7, 2017 - 14:46 -- Open Access
Author(s): 
Rachel F. Daniels, Awa Bineta Deme, Daouda Ndiaye, et al.
Reference: 
Malaria Journal 2017 16:9, 3 January 2017

These findings emphasize the limitations of the RDT used for malaria diagnosis and demonstrate that non-P. falciparum malaria infections occur in Sénégal.

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Limitations of malaria reactive case detection in an area of low and unstable transmission on the Myanmar–Thailand border

November 30, 2016 - 17:22 -- Open Access
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Author(s): 
Daniel M. Parker, Jordi Landier, François H. Nosten, et al.
Reference: 
Malaria Journal 2016 15:571, 25 November 2016

The results of these simulations indicate that reactive case detection for clinical cases using RDTs has limited ability in halting transmission in regions of low and unstable transmission.

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Performance and time to become negative after treatment of three malaria rapid diagnostic tests in low and high malaria transmission settings

October 5, 2016 - 17:39 -- Open Access
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Author(s): 
Francesco Grandesso, Carolyn Nabasumba, Dan Nyehangane, Anne-Laure Page, Mathieu Bastard, Martin De Smet, Yap Boum and Jean-François Etard
Reference: 
Malaria Journal 2016 15:496, 4 October 2016

High transmission contexts and a long time to become negative resulted in considerably reduced specificities for the HRP2 tests.

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A qualitative review of implementer perceptions of the national community-level malaria surveillance system in Southern Province, Zambia

August 9, 2016 - 08:14 -- Open Access
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Author(s): 
Lynne Lohfeld, Tokozile Kangombe-Ngwenya, Anna M. Winters, Zunda Chisha, Busiku Hamainza, Mulakwa Kamuliwo, John M. Miller, Matthew Burns and Daniel J. Bridges
Reference: 
Malaria Journal 2016 15:400, 8 August 2016

This review highlights the importance of a community surveillance system like RCD in shaping Zambia’s malaria elimination campaign by identifying community-based infections that might otherwise remain undetected.

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Integrated paediatric fever management and antibiotic over-treatment in Malawi health facilities: data mining a national facility census

August 8, 2016 - 10:43 -- Open Access
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Author(s): 
Emily White Johansson, Katarina Ekholm Selling, Humphreys Nsona, Bonnie Mappin, Peter W. Gething, Max Petzold, Stefan Swartling Peterson and Helena Hildenwall
Reference: 
Malaria Journal 2016 15:396, 4 August 2016

Integrated paediatric fever management was sub-optimal for completed assessments and antibiotic targeting despite common compliance to malaria treatment guidelines.

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