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artesunate-amodiaquine (ASAQ)

Decreased prevalence of Plasmodium falciparum resistance markers to amodiaquine despite its wide scale use as ACT partner drug in Zanzibar

September 13, 2012 - 13:22 -- Kabogo Ndegwa
Fröberg G, Jörnhagen L, Morris U, Shakely D, Msellem MI, Gil JP, Björkman A, Mårtensson A
Malaria Journal 2012, 11:321 (11 September 2012)

MalariaWorldThis is the first observation of a decreased prevalence of pfcrt 76T, pfmdr1 86Y, 184Y and 1246Y in an African setting after several years of extensive ASAQ use as first-line treatment for uncomplicated malaria.

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