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chloroquine (CQ)-resistance reverser

NOT Open Access | Investigation of 7-benzylidenenaltrexone derivatives as resistance reverser for chloroquine-resistant Plasmodium chabaudi

July 31, 2012 - 07:10 -- Kabogo Ndegwa
Author(s): 
Yoshinori Miyata, Hideaki Fujii, Yuka Uenohara, Seiki Kobayashi, Tsutomu Takeuchi, Hiroshi Nagase
Reference: 
Bioorganic & Medicinal Chemistry Letters, Volume 22, Issue 16, 15 August 2012, Pages 5174–5176

MalariaWorldDerivatives of 7-benzylidenenaltrexone (BNTX), which was recently reported to be an effective chloroquine (CQ)-resistance reverser, were synthesized and evaluated for their CQ-resistance reversing activities.

Medical Condition: 
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