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7β-hydroxy-artemisinin carbamate

Determination of antimalarial compound, ARB-89 (7β-hydroxy-artemisinin carbamate) in rat serum by UPLC/MS/MS and its application in pharmacokinetics

March 13, 2012 - 14:07 -- Patrick Sampao
Deepthi Pabbisetty, Anuradha Illendula, K.M. Muraleedharan, Amar G. Chittiboyina, John S. Williamson, Mitchell A. Avery, Bonnie A. Avery
Journal of Chromatography B, Volumes 889–890, 15 March 2012, Pages 123-129

MalariaWorldThe analysis was carried out on an Acquity™ UPLC BEH C18 column (1.7 μm, 2.1 mm × 50 mm) with a flow rate of 0.3 mL/min. The detection was performed on a triple quadrupole tandem mass spectrometer in positive electrospray ionization (ESI) mode.

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