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7β-hydroxy-artemisinin carbamate

Determination of antimalarial compound, ARB-89 (7β-hydroxy-artemisinin carbamate) in rat serum by UPLC/MS/MS and its application in pharmacokinetics

March 13, 2012 - 14:07 -- Patrick Sampao
Author(s): 
Deepthi Pabbisetty, Anuradha Illendula, K.M. Muraleedharan, Amar G. Chittiboyina, John S. Williamson, Mitchell A. Avery, Bonnie A. Avery
Reference: 
Journal of Chromatography B, Volumes 889–890, 15 March 2012, Pages 123-129

MalariaWorldThe analysis was carried out on an Acquity™ UPLC BEH C18 column (1.7 μm, 2.1 mm × 50 mm) with a flow rate of 0.3 mL/min. The detection was performed on a triple quadrupole tandem mass spectrometer in positive electrospray ionization (ESI) mode.

Technology: 
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