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aspartic protease inhibitors

Role of Plasmodium falciparum Digestive Vacuole Plasmepsins in the Specificity and Antimalarial Mode of Action of Cysteine and Aspartic Protease Inhibitors

December 7, 2009 - 11:51 -- Ingeborg van Schayk
Author(s): 
Pedro A. Moura, John B. Dame, and David A. Fidock
Reference: 
Antimicrob. Agents Chemother. 2009;53 4968-4978

Hemoglobin (Hb) degradation is essential for the growth of the intraerythrocytic stages of malarial parasites.

Medical Condition: 
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