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rapid diagnostic test (RDT)

Spatial heterogeneity can undermine the effectiveness of country-wide test and treat policy for malaria: a case study from Burkina Faso

October 26, 2016 - 17:20 -- Open Access
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Author(s): 
Denis Valle, Justin Millar and Punam Amratia
Reference: 
Malaria Journal 2016 15:513, 19 October 2016

High spatial variability can substantially reduce the effectiveness of a national level test and treat malaria policy.

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Pregnant women and infants as sentinel populations to monitor prevalence of malaria: results of pilot study in Lake Zone of Tanzania

August 8, 2016 - 07:55 -- Open Access
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Author(s): 
Ritha A. Willilo, Fabrizio Molteni, Jeremiah M. Ngondi, et al.
Reference: 
Malaria Journal 2016 15:392, 29 July 2016

Malaria infection was common and well correlated among pregnant women and infants attending routine health services.

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Mass testing and treatment for malaria in low transmission areas in Amhara Region, Ethiopia

June 2, 2016 - 16:30 -- Open Access
Author(s): 
Callie A. Scott, Asnakew K. Yeshiwondim, Asefaw Getachew, et al.
Reference: 
Malaria Journal 2016 15:305, 2 June 2016

In the Ethiopia setting, an MTAT intervention is operationally feasible and can be conducted with high coverage.

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High heterogeneity of malaria transmission and a large sub-patent and diverse reservoir of infection in Wusab As Safil district, Republic of Yemen

April 8, 2016 - 17:11 -- Open Access
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Author(s): 
Jackie Cook, Lynn Grignard, Chris Drakeley, et al.
Reference: 
Malaria Journal 2016 15:193, 8 April 2016

This highly diverse parasite population suggests a high degree of transmissibility and coupled with the substantial proportion of low-density infections, may pose challenges for malaria control and elimination efforts.

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Malaria in children of Tshimbulu (Western Kasai, Democratic Republic of the Congo): epidemiological data and accuracy of diagnostic assays applied in a limited resource setting

February 15, 2016 - 14:35 -- Open Access
Author(s): 
Simona Gabrielli, Livia Bellina, Giovanni Luigi Milardi, Boniface Kabasele Katende, Valentina Totino, Valerio Fullin and Gabriella Cancrini
Reference: 
Malaria Journal 2016 15:81, 11 February 2016

The malaria prevalence among the children and the presence of four Plasmodium species, highlighted in this study, identified a sanitary issue which proved to be more alarming than expected, as it was worsened by the unpredictable presence of P. vivax and Babesia microti (never before reported in DRC).

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High prevalence of asymptomatic malaria infections: a cross-sectional study in rural areas in six departments in Haiti

December 29, 2015 - 15:23 -- Open Access
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Author(s): 
Maha Elbadry, Basima Al-Khedery, John Dame, et al.
Reference: 
Malaria Journal 2015, 14:510 (21 December 2015)

The qRT-PCR assay is sufficiently sensitive to identify an unexpectedly large number of asymptomatic, submicroscopic infections.

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Standardizing Plasmodium falciparum infection prevalence measured via microscopy versus rapid diagnostic test

November 19, 2015 - 06:30 -- Open Access
Author(s): 
Bonnie Mappin, Ewan Cameron, Ursula Dalrymple, Daniel Weiss, Donal Bisanzio, Samir Bhatt, Peter Gething
Reference: 
Malaria Journal 2015, 14:460 (17 November 2015)

The relationships defined in this research can be applied to RDT-derived PfPR data to effectively convert them to an estimate of the parasite prevalence expected using microscopy (or vice versa), thereby standardizing the dataset and improving the signal-to-noise ratio.

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Use of different transmission metrics to describe malaria epidemiology in the highlands of western Kenya

October 27, 2015 - 07:08 -- Open Access
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Author(s): 
Jennifer Stevenson, Gillian Stresman, Chris Drakeley, et al.
Reference: 
Malaria Journal 2015, 14:418 (26 October 2015)

In this highland site in western Kenya malaria transmission was low, but highly heterogeneous.

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Diagnostic performance of a novel loop-mediated isothermal amplification (LAMP) assay targeting the apicoplast genome for malaria diagnosis in a field setting in sub-Saharan Africa

October 13, 2015 - 11:05 -- Open Access
Author(s): 
Eniyou Oriero, Joseph Okebe, Jan Jacobs, Jean-Pierre Van geertruyden, Davis Nwakanma, Umberto D’Alessandro
Reference: 
Malaria Journal 2015, 14:396 (9 October 2015)

The LAMP assay could produce reliable results the same day of the screening.

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A Non-Inferiority, Individually Randomized Trial of Intermittent Screening and Treatment versus Intermittent Preventive Treatment in the Control of Malaria in Pregnancy

August 31, 2015 - 15:39 -- Open Access
Author(s): 
Harry Tagbor, Matthew Cairns, Brian Greenwood, et al.
Reference: 
PLoS ONE 10(8): e0132247

Despite low levels of resistance to SP in the study areas, ISTp-AL performed as well as IPTp-SP.

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