The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10621 malaria professionals are enjoying the free benefits of MalariaWorld today

antibodies

Measurement of naturally acquired humoral immune responses against the C-terminal region of the Plasmodium vivax MSP1 protein using protein arrays

October 26, 2011 - 06:46 -- Kabogo Ndegwa
Author(s): 
Jun-Hu Chen, Yue Wang, Kwon-Soo Ha, Feng Lu, In-Bum Suh, Chae Seung Lim, Jeong Hyun Park, Satoru Takeo, Takafumi Tsuboi & Eun-Taek Han
Reference: 
Parasitology Research, Volume 109, Number 5, 1259-1266

MalariaWorldProtein arrays are powerful tools for antibody profiling and vaccine development against infectious agents. In the previous report, we successfully applied an antibody-based protein array for immunoprofiling of Plasmodium vivax infection.

Medical Condition: 
Medical Treatment: 

Addendum: Recombinant Viral Vaccines Expressing Merozoite Surface Protein-1 Induce Antibody- and T Cell-Mediated Multistage Protection against Malaria

March 22, 2011 - 08:56 -- Kabogo Ndegwa
Author(s): 
Simon J. Draper, Anna L. Goodman, Sumi Biswas, Emily K. Forbes, Anne C. Moore, Sarah C. Gilbert, Adrian V.S. Hill
Reference: 
Cell Host & Microbe, Volume 9, Issue 3, 17 March 2011, Page 252

No abstract available

Medical Condition: 
Medical Treatment: 

Open Access | Plasmodium vivax Sub-Patent Infections after Radical Treatment Are Common in Peruvian Patients: Results of a 1-Year Prospective Cohort Study

February 2, 2011 - 07:10 -- Kabogo Ndegwa
Author(s): 
Peter Van den Eede, Veronica E. Soto-Calle, Christopher Delgado, Dionicia Gamboa, Tanilu Grande, Hugo Rodriguez, Alejandro Llanos-Cuentas, Jozef Anné, Umberto D'Alessandro, Annette Erhart
Reference: 
PLoS ONE 6(1): e16257

In Peru, the P. vivax recurrent infections were common and displayed a high turnover of parasite genotypes compared to day 0.

Country: 
Medical Condition: 
Medical Treatment: 

Open Access | Distinct patterns of blood-stage parasite antigens detected by plasma IgG subclasses from individuals with different level of exposure to Plasmodium falciparum infections

October 30, 2010 - 12:17 -- Kabogo Ndegwa
Author(s): 
Olesen C, Brahimi K, Vandahl B, Lousada-Dietrich S, Jogdand PS, Vestergaard LS, Dodoo D, Hojrup P, Christiansen M, Larsen S, Singh S, Theisen M
Reference: 
Malaria Journal 2010, 9:296 (26 October 2010)

In the present study, there was no evidence for switching of antibody responses from non-cytophilic to cytophilic subclasses against blood-stage parasite antigens as a likely mechanism for induction of protective immunity against malaria.

Medical Condition: 
Medical Treatment: 

Host Response and Inflamation: Hierarchical, Domain Type-Specific Acquisition of Antibodies to Plasmodium falciparum Erythrocyte Membrane Protein 1 in Tanzanian Children

October 22, 2010 - 12:25 -- Patrick Sampao
Author(s): 
Gerald K., Louise T., et al.
Reference: 
Infect. Immun., Nov 2010; 78: 4653 - 4659.

The results imply that anti-PfEMP1 antibodies effectively structure PfEMP1 expression and play a major role in limiting parasite multiplication in the blood.

Country: 
Medical Condition: 
Medical Treatment: 

Open Access | Epitope mapping of PfCP-2.9, an asexual blood-stage vaccine candidate of Plasmodium falciparum

April 15, 2010 - 11:50 -- Kabogo Ndegwa
Author(s): 
Li C, Wang R, Wu Y, Zhang D, He Z, Pan W
Reference: 
Malaria Journal 2010, 9:94 (12 April 2010)

This study provided valuable information on epitopes of PfCP-2.9 vaccine candidate through generation of a panel of mAbs and a series of PfCP-2.9 mutants. The information may prove to be useful for designing more effective malaria vaccines against blood-stage parasites.

Technology: 
Medical Condition: 

Inhibition of Erythrocyte Invasion and Plasmodium falciparum Merozoite Surface Protein 1 Processing by Human Immunoglobulin G1 (IgG1) and IgG3 Antibodies

December 7, 2009 - 11:26 -- Ingeborg van Schayk
Author(s): 
Maria Lazarou, Jose A. Guevara Patino, Richard M. Jennings, Richard S. McIntosh, Jianguo Shi, Steven Howell, Eilish Cullen, Tarran Jones, Jaime R. Adame-Gallegos, Jonathan A. Chappel, Jana S. McBride, Michael J. Blackman, Anthony A. Holder, and Richard J. Pleass
Reference: 
Infect. Immun. 2009;77 5659-5667

Antigen-specific antibodies (Abs) to the 19-kDa carboxy-terminal region of Plasmodium falciparum merozoite surface protein 1 (MSP119) play an important role in protective immunity to malaria.

Medical Condition: 
Subscribe to RSS - antibodies