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Open Access | Disruption of plasmepsin-4 and merozoites surface protein-7 genes in Plasmodium berghei induces combined virulence-attenuated phenotype

October 31, 2011 - 14:59 -- Patrick Sampao
Roberta Spaccapelo, Elena Aime, Sara Caterbi, Paola Arcidiacono, Barbara Capuccini, Manlio Di Cristina,Tania Dottorini, Mario Rende, Francesco Bistoni & Andrea Crisanti
Scientific Reports Volume: 1:39

MalariaWorldThese observations provide a proof-of-concept step for the development of human malaria vaccines based on genetically attenuated blood-stage parasites.

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