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platinum (II)

4-aminoquinoline analogues and its platinum (II) complexes as antimalarial agents

October 19, 2011 - 14:27 -- Patrick Sampao
Author(s): 
Nicolli Bellotti de Souza, Arturene M.L. Carmo, Clarice Abramo, et al.
Reference: 
Biomedicine & Pharmacotherapy, Volume 65, Issue 4, July 2011, Pages 313-316

MalariaWorldThese compounds were tested in vivo in a murine model and revealed remarkable inhibition of parasite multiplication values, whose majority ranged from 50 to 80%. In addition they were not cytotoxic. Thus, they may be object of further research for new antimalarial agents.

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