The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10481 malaria professionals are enjoying the free benefits of MalariaWorld today

apical membrane

Apical Membrane Antigen 1 as an Anti-Malarial Drug Target

August 3, 2011 - 09:02 -- Patrick Sampao
A. MacRaild, Christopher; F. Anders, Robin; Foley, Michael; S. Norton, Raymond
Current Topics in Medicinal Chemistry, Volume 11, Number 16, August 2011 , pp. 2039-2047(9)

Here we review both the structural details and functional significance of interactions at the hydrophobic cleft of AMA1, and argue that this feature of the protein represents an excellent target for the development of drugs that would block host cell invasion by malarial parasites.

Subscribe to RSS - apical membrane