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phosphoribosyltransferase

6-Oxopurine Phosphoribosyltransferase: A Target for the Development of Antimalarial Drugs

August 2, 2011 - 14:05 -- Patrick Sampao
Author(s): 
de Jersey, John; Holy, Antonin; Hockova, Dana; Naesens, Lieve; T. Keough, Dianne; W. Guddat, Luke
Reference: 
Current Topics in Medicinal Chemistry, Volume 11, Number 16, August 2011 , pp. 2085-2102(18)

The focus of this review is on the identification and characterization of inhibitors of the enzymes from both Pf and Pv as antimalarial drug leads.

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