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immunoepidemiology

Malaria Immunoepidemiology in Low Transmission: Correlation of Infecting Genotype and Immune Response to Domains of Plasmodium falciparum Merozoite Surface Protein 3

April 23, 2011 - 08:47 -- Patrick Sampao
Author(s): 
Stephen J. Jordan, Ana L. Oliveira, Jean N. Hernandez, Robert A. Oster, Debasish Chattopadhyay, OraLee H. Branch, and Julian C. Rayner
Reference: 
Infect. Immun., May 2011; 79: 2070 - 2078.

Evidence for cross-reactive responses was much stronger when variants within one allele class were tested, which has implications for the rational development of genotype-transcending PfMSP3-based vaccines.

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