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Open Access | Dendritic Cells and Hepatocytes Use Distinct Pathways to Process Protective Antigen from Plasmodium in vivo

March 22, 2011 - 09:04 -- Kabogo Ndegwa
Author(s): 
Ian A. Cockburn, Sze-Wah Tse, Andrea J. Radtke, Prakash Srinivasan, Yun-Chi Chen, Photini Sinnis, Fidel Zavala
Reference: 
PLoS Pathog 7(3): e1001318

Malaria-protective CD8+ T cells specific for the circumsporozoite (CS) protein are primed by dendritic cells (DCs) after sporozoite injection by infected mosquitoes.

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