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PfGCHI

Co-expression of the Plasmodium falciparum molecular chaperone, PfHsp70, improves the heterologous production of the antimalarial drug target GTP cyclohydrolase I, PfGCHI

March 14, 2011 - 10:01 -- Patrick Sampao
Author(s): 
Linda L. Stephens, Addmore Shonhai, Gregory L. Blatch
Reference: 
Protein Expression and Purification, Volume 77, Issue 2, June 2011, Pages 159-165

This is the first report of a heterologous co-expression system in which a plasmodial chaperone is harnessed for the improved production and purification of a plasmodial target protein.

Medical Condition: 
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